1003013-11-3

Upstream product

• 13380-85-3 4-hydroxymethylcyclohexanecarboxylic acid methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1003013-12-4 4-(3-nitro-pyrazol-1-ylmethyl)-cyclohexanecarboxylic acid methyl ester 
• 1003013-13-5 4-(3-amino-pyrazol-1-ylmethyl)-cyclohexanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

NEW BENZIMIDAZOLE DERIVATIVES

The present invention relates to compounds of formula (I), as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A, B, R1, R2, R3, R4, R5, n, m and p have the significance defined herein.

NEW BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS FXR AGONISTS

Compounds of formula (I) as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A, B, R1, R2, R3, R4, R5, n, m and p have the significance given in claim 1.

Pyrazole glucokinase activators

Disclosed herein are pyrazole glucokinase activators of the formula (I) useful for the treatment of metabolic diseases and disorders, preferably diabetes mellitus.