10035-85-5Relevant academic research and scientific papers
Deacylation of esters, thioesters and amides by a naphthalene-catalysed lithiation
Behloul, Cherif,Guijarro, David,Yus, Miguel
, p. 309 - 314 (2006)
The reaction of different esters, thioesters and amides derived from pivalic, benzoic and 4-tert-butylbenzoic acids with an excess of lithium and a catalytic amount of naphthalene (8 mol%) led, after methanolysis, to the corresponding alcohols, thiols and amines, respectively, through a reductive non-hydrolytic procedure. This methodology represents a reasonable alternative to other non-reductive protocols. Georg Thieme Verlag Stuttgart.
A simple acylation of thiols with anhydrides
Temperini, Andrea,Annesi, Diego,Testaferri, Lorenzo,Tiecco, Marcello
supporting information; experimental part, p. 5368 - 5371 (2010/10/20)
Different thiols were efficiently acylated at room temperature with different anhydrides in the presence of potassium carbonate. Chemoselective protection of thiol in the presence of hydroxy group was achieved using di-tert-butyl dicarbonate and isatoic anhydride.
Direct transformation of carboxyclic acids to thiol esters induced by phenyl dichlorophosphate
Liu, Hsing-Jang,Sabesan, Subramaniam Iyer
, p. 2645 - 2648 (2007/10/02)
The condensation of carboxylic acids and thiols is greatly facilitated by the use of phenyl dichlorophosphate as an activating agent giving thiol esters in good yields.
