1003576-69-9Relevant academic research and scientific papers
Novel acyl coenzyme A (CoA): Diacylglycerol acyltransferase-1 inhibitors: Synthesis and biological activities of diacylethylenediamine derivatives
Nakada, Yoshihisa,Aicher, Thomas D.,Huerou, Yvan Le,Turner, Timothy,Pratt, Scott A.,Gonzales, Stephen S.,Boyd, Steve A.,Miki, Hiroshi,Yamamoto, Toshihiro,Yamaguchi, Hiroshi,Kato, Koki,Kitamura, Shuji
experimental part, p. 2785 - 2795 (2010/07/04)
A series of diacylethylenediamine derivatives were synthesized and evaluated for their inhibitory activity against DGAT-1 and pharmacokinetic profile to discover new small molecule DGAT-1 inhibitors. Among the compounds, N-[2-({[1-phenyl-3-(trifluoromethy
AMIDE COMPOUNDS
-
Page/Page column 204; 209-210, (2008/06/13)
The present invention provides compounds represented by the formula (Ia) the formula (Ib) the formula (Ic) and the formula (Id) wherein each symbol is as defined in the specification. According to the present invention, these compounds have a DGAT inhibit
