1003858-66-9

Basic information

• Product Name: 4-fluoro-1H-indol-5-amine
• Synonyms: 4-fluoro-1H-indol-5-amine
• CAS NO: 1003858-66-9
• Molecular Formula: C₈H₇FN₂
• Molecular Weight: 150.1529832
• Mol File: 1003858-66-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 337.9±22.0 °C(Predicted)
• Appearance: /
• Density: 1.385±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 16.79±0.30(Predicted)
• CAS DataBase Reference: 4-fluoro-1H-indol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluoro-1H-indol-5-amine(1003858-66-9)
• EPA Substance Registry System: 4-fluoro-1H-indol-5-amine(1003858-66-9)

Safety Data

• Hazardous Substances Data: 1003858-66-9(Hazardous Substances Data)

Upstream product

• 1003858-68-1 4-fluoro-5-nitro-2,3-dihydro-1H-indole 
• 1003858-67-0 1-(4-fluoro-5-nitro-2,3-dihydroindol-1-yl)ethanone 
• 860024-83-5 1-(4-fluoroindolin-1-yl)ethanone 
• 552866-98-5 2,3-dihydro-4-fluoro-1H-indole 
• 387-43-9 4-fluoroindole 

Relevant articles and documents

5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES

The invention is directed to substituted salicylamide derivatives. Specifically, the invention is directed to compounds according to Formula (I): wherein R, R1 and R2 are as defined herein, or a pharmaceutically acceptable salt thereof. The compounds of the invention are inhibitors of CD73 and can be useful in the treatment of cancer, pre-cancerous syndromes and diseases associated with CD73 inhibition, such as AIDS, the treatment of HIV, autoimmune diseases, infections, atherosclerosis, and ischemia–reperfusion injury. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting CD73 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.