100388-04-3Relevant academic research and scientific papers
BENZOIC ACID COMPOUNDS AND USE THEREOF AS MEDICAMENTS
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, (2008/06/13)
Benzoic acid compounds of the formula STR1 wherein each symbol is as defined in the specification, optical isomers thereof and pharmaceutically acceptable salts thereof; pharmaceutical composition comprising this compound and pharmaceutically acceptable additive; and serotonin 4 receptor agonists, gastrointestinal prokinetic agents and therapeutic agents for various gastrointestinal diseases, which comprise this compound as active ingredient. The compounds of the present invention have high and selective affinity for serotonin 4 receptor, and show agonistic effects thereon. Accordingly, they are useful medications for the prophylaxis and treatment of various gastrointestinal diseases, central nervous disorders, cardiac function disorders, urinary diseases, and the like, as well as useful anti-nociceptors for analgesic use which increase threshold of pain.
Dipeptides as renin inhibitors
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, (2008/06/13)
Dipeptides are described which are represented by the formula STR1 wherein the various substituents are defined hereinbelow. These compounds have a strong inhibitory efect on human renin, and are useful as a therapeutically active agent for the treatment of hypertension, especially renin-associated hypertension.
Derivatives of substituted N-alkylimidazoles
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, (2008/06/13)
Compounds useful as anticonvulsant agents, antifungals and antibacterials are represented by the formula STR1 wherein R1 is phenyl optionally substituted by one or more substituents selected from the group consisting of halo, lower alkyl of one
