100389-85-3Relevant academic research and scientific papers
Nucleophilic addition of α-(dimethylsilyl)nitriles to aldehydes and ketones
Jinzaki, Takaaki,Arakawa, Mitsuru,Kinoshita, Hidenori,Ichikawa, Junji,Miura, Katsukiyo
supporting information, p. 3750 - 3753 (2013/08/23)
α-Alkylated (dimethylsilyl)acetonitriles (Me2HSiCR 3R4CN) react spontaneously with aldehydes in DMSO to give β-hydroxynitriles in good to high yields. The addition to ketones is effectively promoted by using MgCl2/su
Alkyliron and Alkylcobalt Reagents, IV.- Aldehyde-Selective Cyanoalkylation with Cyanalkyl Derivatives of Iron(II) and Other Transition Metals
Kauffmann, Thomas,Kieper, Hansjoerg,Pieper, Hans
, p. 899 - 906 (2007/10/02)
For the transfer of the cyanomethyl residue with high aldehydes vs. ketone selectivity, the Fe reagent 3a is a good alternative to the known Ti reagent 1a, whereas analogous reagents with the metals Mn, Co, Ni or Cu are unfavorable.For the aldehyde- vs. k
