934-69-0

Usage

Uses

Used in Organic Synthesis:
4-Methylidenecyclohexane-1-carboxylic acid is used as a building block in organic synthesis for the development of various chemical compounds and pharmaceuticals. Its unique structure allows for versatile chemical reactions, making it a valuable intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Methylidenecyclohexane-1-carboxylic acid is used as a key intermediate in the synthesis of various drug molecules. Its ability to participate in a wide range of chemical reactions enables the creation of diverse therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
4-Methylidenecyclohexane-1-carboxylic acid is also utilized in chemical research as a model compound for studying various organic reactions and mechanisms. Its unique structure provides researchers with opportunities to explore new synthetic pathways and develop innovative methodologies in organic chemistry.

Upstream product

• 145576-28-9 ethyl 4-methylidenecyclohexanecarboxylate 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 

Downstream Products

• 1004-24-6 4-methylene-1-cyclohexanemethanol 
• 874-61-3 4-oxocyclohexanecarboxylic acid 
• 76825-09-7 (4-Methylenecyclohexylmethyl)bromide 
• 1228182-62-4 Methanesulfonic acid 4-methylene-cyclohexylmethyl ester 
• 1420294-77-4 4-methylenecyclohexanecarboxamide 
• 1420294-78-5 benzyl 4-methylenecyclohexylmethylcarbamate 
• 1420294-79-6 benzyl spiro[2.5]octan-6-ylmethylcarbamate 
• 854444-57-8 C-(4-methylene-cyclohexyl)-methylamine 

Relevant academic research and scientific papers

NOVEL COMPOUNDS

Novel rapamycin analogues and methods for their production with FKBP and/or MIP inhibitory activity with reduced mTOR inhibitory activity with therapeutic potential e.g. as bacterial virulence inhibitors.

Hepatitis C Virus Inhibitors

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS

The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.

9-AMINOMETHYL SUBSTITUTED TETRACYCLINE COMPOUND

The present invention relates to 9-aminomethyl substituted tetracycline compounds represented by formula (I), or pharmaceutically acceptable salt, prodrug, solvate or isomer thereof, as well as a method for preparing these compounds and a pharmaceutical composition comprising the same. The present invention relates also to a use of these compounds in the preparation of a medicament for the treatment and/or prophylaxis of tetracycline drug-sensitive disease. wherein, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R7, R8, R9a, R9b, R10, R11, R12, R13a and R13b are each independently as defined in the description.

Antiparasitic agents

The invention provides novel compounds having the formula: STR1 wherein R when taken individually is H; R1 when taken individually is H or OH; R and R1 when taken together represent a double bond; R2 is an alpha-branched C3 -C8 alkyl, alkenyl, alkynyl, alkoxyalkyl or alkylthioalkyl group; a C3 -C8 cycloalkyl, C5 -C8 cycloalkenyl or C5 -C8 cycloalkylalkyl group, any of which may be substituted by methylene or one or more C1 -C4 alkyl groups or halo atoms; or a 3 to 6 membered oxygen or sulphur containing heterocyclic ring which may be substituted by one or more C1 -C4 alkyl groups or halo atoms; R3 is hydrogen or methyl; R4 is H or 4'-(alpha-L-oleandrosyl)-alpha-L-oleandrosyloxy with the proviso that when R2 is alkyl it is not isopropyl or sec-butyl; when R4 is H, each of R and R1 is H, and R2 is not methyl or ethyl; and when R4 is H, R is H, R1 is OH, and R2 is not 2-buten-2-yl, 2-penten-2-yl or 4-methyl-2-penten-2-yl. The compounds are broad spectrum antiparasitic agents having utility as anthelmintics, ectoparasiticides, insecticides and acaricides. The invention also provides a process for producing the novel avermectin and milbemycin derivatives by adding a carboxylic acid or derivative thereof to a fermentation of an avermectin or milbemycin producing organism.