76825-09-7 Usage
Uses
Used in Organic Synthesis:
1-(Bromomethyl)-4-methylidenecyclohexane is used as a synthetic intermediate for the creation of more complex organic molecules. Its reactive bromomethyl group allows for further functionalization and the formation of new chemical bonds, making it a valuable building block in organic chemistry.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-(Bromomethyl)-4-methylidenecyclohexane is used as a key component in the development of new drugs. Its unique structure can be modified to target specific biological pathways or to improve the pharmacokinetic properties of drug candidates, potentially leading to more effective treatments.
Used in Material Science:
1-(Bromomethyl)-4-methylidenecyclohexane is utilized as a precursor in the synthesis of advanced materials. Its structural features can be incorporated into polymers, coatings, or other materials to enhance their properties, such as stability, reactivity, or biocompatibility.
It is important to handle 1-(Bromomethyl)-4-methylidenecyclohexane with care due to the reactivity of the bromomethyl group, which can pose potential hazards. Proper safety measures should be taken to ensure the safe use of 1-(Bromomethyl)-4-methylidenecyclohexane in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 76825-09-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,8,2 and 5 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 76825-09:
(7*7)+(6*6)+(5*8)+(4*2)+(3*5)+(2*0)+(1*9)=157
157 % 10 = 7
So 76825-09-7 is a valid CAS Registry Number.
76825-09-7Relevant academic research and scientific papers
Synthesis of Bridgehead-Substituted Bicycloheptanes by Radical Cyclization
Della, Ernest W.,Knill, Andrew M.,Pigou, Paul E.
, p. 2110 - 2114 (2007/10/02)
A kinetic investigation shows that the rate of cyclization (kC) of the (4-methylenecyclohexyl)methyl radical 3 at 25 deg C is 4.4 x 102 s-1, which is considerably slower than that (2.3 x 105 s-1) of the parent 5-hexenyl radical.The energy of activation for the process 3 -> 4 is 12.8 kcal mol-1, which is in excellent agreement with theoretical values derived from force-field calculations.Ring-closure of appropriately substituted (4-methylenecyclohexyl)methyl radical precursors allows the synthesis of bicycloheptyl systems with useful functionality at the bridgehead to be achieved readily and in high yield.An interesting example is given of the application of an iodine-atom-transfer cyclization to the synthesis of a bicycloheptane functionalized at C7 and C1.
