100400-22-4Relevant academic research and scientific papers
New chiral iodooxazoline catalysts for the I(III)-mediated α-tosyloxylation of ketones: Refining the stereoinduction model
Therien, Marie-Eve,Guilbault, Audrey-Anne,Legault, Claude Y.
, p. 1193 - 1197 (2013)
A new family of iodooxazoline catalysts, derived from widely available chiral ketones (menthone and camphor), was developed to promote the iodine(III)-mediated α-tosyloxylation of ketone derivatives. The reaction conditions to achieve the direct formation
Absolute configuration of ketone cyanohydrins by 1H nmr: The special case of polar substituted tertiary alcohols
Louzao, Iria,Garcia, Rosa,Seco, Jose Manuel,Quinoa, Emilio,Riguera, Ricardo
supporting information; experimental part, p. 53 - 56 (2009/07/04)
The absolute configuration of ketone cyanohydrins can be assigned from analysis of the 1H NMR spectra of the corresponding (R)-and (S)-MPA ester derivatives and use of ΔδRS signs. This is an application of the NMR methodology for ste
Robust and efficient, yet uncatalyzed, synthesis of trialkylsilyl-protected cyanohydrins from ketones
Cabirol, Fabien L.,Lim, Angela E. C.,Hanefeld, Ulf,Sheldon, Roger A.,Lyapkalo, Ilya M.
, p. 2446 - 2449 (2008/09/19)
(Chemical Equation Presented) High-yielding cyanosilylation of ketones with NaCN and various chlorotrialkylsilanes in DMSO proceeds smoothly without catalysis to give silyl-protected ketone cyanohydrins. The unique role of DMSO consists in rendering naked
