100420-03-9Relevant academic research and scientific papers
HIGHLY ENANTIOSELECTIVE SYNTHESIS OF ANTI(THREO)-ALDOLS BY THE ASYMMETRIC ALDOL REACTION UTILIZING A CHIRAL AZAENOLATE
Narasaka, Koichi,Miwa, Tetsuo
, p. 1217 - 1220 (1985)
Diastereo- and enantioselective aldol reaction between 3-pentanone and aldehydes is achieved utilizing a chiral oxazolidine derived from 3-pentanone and chiral norephedrine.The reaction of a tin(II) azaenolate generated from the chiral oxazolidine with aldehydes affords predominantly anti(threo)-aldols of high enantiomeric purity.
