100428-67-9

Upstream product

• 42537-02-0 2-<(Z)-2-pentenyl>cyclopentanone 
• 87611-61-8 (Z)-5-Hydroxy-dec-7-enoic acid 
• 25448-66-2 6-(2-pentynyl)-tetrahydro-2-pyranone 
• 100-73-2 acrolein dimer 
• 3749-36-8 2-hydroxymethyl-3,4-dihydro-2H-pyran 
• 111-30-8 Glutaraldehyde 
• 10316-66-2 2-hydroxy-2-cyclohexen-1-one 
• 87086-46-2 6-(2-pentynyl)-2-hydroxy-2-cyclohexen-1-one 
• 87086-50-8 3-(2-pentynyl)-2-hydroxy-2-cyclohexen-1-one 
• 87086-47-3 6-<(Z)-2-pentenyl>-2-hydroxy-2-cyclohexen-1-one 
• 87086-51-9 3-<(Z)-2-pentenyl>-2-hydroxy-2-cyclohexen-1-one 
• 72666-29-6 5-oxo-7-decynoic acid 
• 87086-53-1 5-oxo-(Z)-7-decenoic acid 
• 87086-56-4 5-Hydroxy-dec-7-ynoic acid 

Downstream Products

• 136173-93-8 (R)-(-)-jasmine lactone 
• 136173-91-6 (6S)-(+)-jasmine lactone 

Relevant academic research and scientific papers

Compounds having protected hydroxy groups

The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.

Compounds having protected hydroxy groups

The present invention relates to compounds with protected hydroxy groups of formula (I) These compounds are precursors for organoleptic agents, such as fragrances, and masking agents and for antimicrobial agents. When activated, the compounds of formula (I) are cleaved and form one or more organoleptic and/or antimicrobial compounds.

Precursor compounds

The compounds of the formula I are precursors for organoleptic and antimicrobial compounds. The latter are generated in the presence of skin bacteria, enzymes or acidic or alkaline conditions. One precursor molecule can provide one or more different compounds.

Beta-ketoester compounds

The beta-ketoesters of formula I are useful as precursors for organoleptic compounds, especially for flavors, fragrances and masking agents and antimicrobial compounds.

NEW SYNTHESIS OF JASMINE LACTONE AND RELATED δ-LACTONES FROM 3-SUBSTITUTED 1,2-CYCLOHEXANEDIONES BY USE OF DYE-SENSITIZED PHOTOOXYGENATION

A new synthesis of jasmine lactone and related δ-lactones is described which uses a novel dye-sensitized photooxygenation of 3-(2-alkenyl)- or 3-(2-alkynyl)-1,2-cyclohexanediones as a key step.

BAEYER-VILLIGER OXIDATION WITH Me3SiOOSiMe3 UNDER ASSISTANCE OF SnCl4 OR BF3-OEt2.

Treatment of ketones with bis(trimethylsilyl) peroxide and Lewis acid such as SnCl//4 or BF//3-OEt//2 in dichloromethane at room temperature affords esters in fair to excellent yields. Jasmine lactone is synthesized from 2- left bracket (Z)-pentenyl right bracket cyclopentanine by means of Me//3SiOOSiMe//3-BF//3-OEt//2 system without any protection of the carbon-carbon double bond. The oxidation of enol acetates of ketones to alpha -hydroxy (or alpha -acetoxy) ketones with Me//3SiOOSiMe//3-FeCl//3 system is also disclosed.