1004292-98-1 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3aR,7aS)-Octahydro-1H-indole-2-carboxylic acid hydrochloride is used as an intermediate in the synthesis of Perindoprilat (P287530), an angiotensin-converting enzyme (ACE) inhibitor. It plays a crucial role in the development of antihypertensive medications, which are essential for treating high blood pressure and related cardiovascular conditions.
The compound's specific configuration and functional groups make it a valuable building block for the creation of complex drug molecules, contributing to the advancement of novel therapeutic agents in the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 1004292-98-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,4,2,9 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1004292-98:
(9*1)+(8*0)+(7*0)+(6*4)+(5*2)+(4*9)+(3*2)+(2*9)+(1*8)=111
111 % 10 = 1
So 1004292-98-1 is a valid CAS Registry Number.
1004292-98-1Relevant academic research and scientific papers
PROCESSES FOR THE SYNTHESIS OF (2S, 3AR, 7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL
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, (2011/02/24)
Processes for the preparation of (2S, 3aR, 7aS) -octahydro-1H-indole-20carboxylic acid hydrochloride starting from (1S, 2S) -2- [ (S) -1- phenylethyl amino] cyclohexyl) methanol are described.
Process for the preparation of perindopril and salts thereof
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Page/Page column 11, (2008/06/13)
The present invention describes a novel method for the synthesis of (2S,3aS,7aS)-octahydroindole-2-carboxylic acid, or of one of its aryl esters of formula XIII wherein X and Y are a hydrogen atom, a halogen, alkyl, alkoxyl or nitro group, and the conversion of the paranitrobenzyl ester of formula X into Perindopril of formula I or one of its salts.
