191986-95-5

Upstream product

• 191986-93-3 (1R,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 53898-03-6 2-(S-1-phenylethylamino)-cyclohex-1-enecarboxylic acid ethyl ester 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 1346773-51-0 (1S,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate hydrochloride 
• 1346773-51-0 (1R,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate hydrochloride 

Downstream Products

• 1346773-51-0 (1S,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate hydrochloride 
• 213993-31-8 (1S,2S)-2-amino-cyclohexylmethanol 
• 145641-35-6 phenylmethyl-(2S,3aR,7aS)-octahydroindole-2-carboxylate hydrochloride 
• 1260890-62-7 (1S,2S)-2-[(S)-1-phenylethylamino]cyclohexylmethanol 
• 1260890-64-9 ethyl 2-(((1S,2S)-2-(hydroxymethyl)cyclohexyl)((S)-1-phenylethyl)amino)acetate 
• 1260890-68-3 ethyl 2-(((1S,2S)-2-((methylsulfonyloxy)methyl)cyclohexyl)((S)-1-phenylethyl)amino)acetate 
• 1260890-69-4 (2S,3aR,7aS)-ethyl 1-((S)-1-phenylethyl)octahydro-1H-indole-2-carboxylate 
• 144540-75-0 (2S,3aR,7aS)-octahydro-1H-indole-2-carboxylic acid hydrochloride 
• 312965-07-4 (S,S)-trans-N-(9-fluorenylmethoxycarbonyl)-2-aminocyclohexanecarboxylic acid 
• 5691-19-0 rac-trans-2-aminocyclohexanecarboxylic acid 

Relevant academic research and scientific papers

PROCESSES FOR THE SYNTHESIS OF (2S, 3AR, 7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL

Processes for the preparation of (2S, 3aR, 7aS) -octahydro-1H-indole-20carboxylic acid hydrochloride starting from (1S, 2S) -2- [ (S) -1- phenylethyl amino] cyclohexyl) methanol are described.

Asymmetric synthesis of a new helix-forming β-amino acid: trans-4-aminopiperidine-3-carboxylic acid

We report a synthesis of a protected derivative of trans-4aminopiperidine-3-carboxylic acid (APiC). The route provides either enantiomer. All intermediates are purified by crystallization, and large-scale preparation is therefore possible. An analogous ro

A practical synthesis of enantiopure ethyl cis-2-amino-1-cyclohexanecarboxylate via asymmetric reductive amination methodology

A simple and practical method for large scale preparation of optically pure ethyl 2-amino-1-cyclohexanecarboxylate was developed via a reductive amination of 2-oxo-cyclohexanecarboxylate with a chiral α-methylbenzylamine. The major diastereomer was isolat