53898-03-6

Upstream product

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 

Downstream Products

• 136118-25-7 (S)-1-(2-tert-Butoxycarbonyl-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 348135-64-8 (R)-1-(2-tert-Butoxycarbonyl-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 69881-57-8 (+)-(R)-2-Oxo-1-(3-oxo-1-butyl)-cyclohexancarbonsaeureaethylester 
• 69881-58-9 (-)-(S)-2-Oxo-1-(3-oxo-1-butyl)-cyclohexancarbonsaeureaethylester 
• 72763-87-2 ethyl (R)-1-(prop-2-enyl)-2-oxocyclohexanecarboxylate 
• 58648-10-5 ethyl (S)-1-allyl-2-oxocyclohexane-1-carboxylate 
• 152614-57-8 (R)-1-(2-Cyano-ethyl)-2-oxo-cyclohexanecarboxylic acid ethyl ester 
• 116831-08-4 (R)-ethyl cyclohexanone-2-(2-carboethoxy-ethyl)-2-carboxylate 
• 116831-06-2 (S)-ethyl cyclohexanone-2-(2-carboethoxy-ethyl)-2-carboxylate 
• 191986-94-4 (1S,2R)-2-((S)-1-Phenyl-ethylamino)-cyclohexanecarboxylic acid ethyl ester 
• 191986-93-3 (1R,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate 
• 5691-19-0 rac-trans-2-aminocyclohexanecarboxylic acid 
• 191986-95-5 (1S,2S)-ethyl 2-((S)-1-phenylethylamino)cyclohexanecarboxylate 
• 312965-07-4 (S,S)-trans-N-(9-fluorenylmethoxycarbonyl)-2-aminocyclohexanecarboxylic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of a new helix-forming β-amino acid: trans-4-aminopiperidine-3-carboxylic acid

We report a synthesis of a protected derivative of trans-4aminopiperidine-3-carboxylic acid (APiC). The route provides either enantiomer. All intermediates are purified by crystallization, and large-scale preparation is therefore possible. An analogous ro

PROCESSES FOR THE SYNTHESIS OF (2S, 3AR, 7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL

Processes for the preparation of (2S, 3aR, 7aS) -octahydro-1H-indole-20carboxylic acid hydrochloride starting from (1S, 2S) -2- [ (S) -1- phenylethyl amino] cyclohexyl) methanol are described.

SUBSTITUTED SPIRO AZABICYCLICS AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present application describes modulators of CCR3 of formula (Ia) and (Ib): (I) or pharmaceutically acceptable salt forms thereof, wherein Z, R1, R2, R3, R4, R5, R5', R6, a, b

A practical synthesis of enantiopure ethyl cis-2-amino-1-cyclohexanecarboxylate via asymmetric reductive amination methodology

A simple and practical method for large scale preparation of optically pure ethyl 2-amino-1-cyclohexanecarboxylate was developed via a reductive amination of 2-oxo-cyclohexanecarboxylate with a chiral α-methylbenzylamine. The major diastereomer was isolat

Facile enantioselective synthesis of two new bicyclic chiral templates

Optically active bicyclic dienes, 4 and 5 have been enantioselectively prepared in three and four steps, respectively. Mixtures of predominantly either the R or S enantiomer were obtained via an asymmetric alkylation of a chiral enamine.

Synthesis of optically active α,α-distubstituted β-keto esters via chiral β-enamino esters

Michael addition of chiral β-enamino esters to MVK and acrylates promoted by Lewis acids (ZnCl2, MgBr2) or high pressure (11-14 Kbar) afforded, after hydrolytic work-up, α,α-disubstituted β-keto esters in good enantiomeric carbon exc