10045-65-5

Basic information

• Product Name: 1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE
• Synonyms: 1-Benzylimidazole-2-carboxaldehyde;Imidazole-2-carboxaldehyde, 1-benzyl-;1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE;1-BENZYL-2-FORMYLIMIDAZOLE;1H-Imidazole-2-carboxaldehyde, 1-(phenylmethyl)-;1-(benzyl)imidazole-2-carbaldehyde;1-(phenylmethyl)-2-imidazolecarboxaldehyde;1-(phenylmethyl)imidazole-2-carbaldehyde
• CAS NO: 10045-65-5
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.21
• Mol File: 10045-65-5.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 384.2°Cat760mmHg
• Flash Point: 186.2°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 4.15E-06mmHg at 25°C
• Refractive Index: 1.592
• CAS DataBase Reference: 1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE(10045-65-5)
• EPA Substance Registry System: 1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE(10045-65-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 10045-65-5(Hazardous Substances Data)

Usage

General Description

1-Benzyl-1H-imidazole-2-carbaldehyde is a chemical compound with the molecular formula C11H10N2O. It is an organic compound containing an imidazole ring and a benzyl group, with a carbonyl group attached. 1-BENZYL-1H-IMIDAZOLE-2-CARBALDEHYDE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has potential applications in the development of new drugs due to its structural characteristics and chemical reactivity. Additionally, it has been studied for its antimicrobial and antifungal properties, making it a valuable compound for medicinal and agricultural research.

InChI:InChI=1/C11H10N2O/c14-9-11-12-6-7-13(11)8-10-4-2-1-3-5-10/h1-7,9H,8H2

Upstream product

• 100-39-0 benzyl bromide 
• 5376-10-3 1-benzyl-2-(hydroxymethyl)imidazole 
• 288-32-4 1H-imidazole 
• 100-44-7 benzyl chloride 
• 10111-08-7 2-imidazolecarbaldehyde 
• 4238-71-5 1-benzylimidazole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 20062-64-0 1-benzyl-1H-imidazole-2-carbaldehyde thiosemicarbazone 
• 99809-02-6 2-(tert-butyldimethylsiloxy)-2-(1-benzyl-2-imidazolyl)thioacetamide 
• 99809-09-3 2-[(1-Benzyl-1H-imidazol-2-yl)-(tert-butyl-dimethyl-silanyloxy)-methyl]-4-(2-methyl-1H-imidazol-4-yl)-thiazole; hydrobromide 
• 1352710-08-7 C₂₁H₂₉N₃ 
• 1394248-59-9 (E)-2-(2-((1-benzyl-1H-imidazol-2-yl)methylene)hydrazinyl)-N-(3-morpholinopropyl)quinazolin-4-amine 
• 1394248-63-5 (E)-2-(2-((1-benzyl-1H-imidazol-2-yl)methylene)hydrazinyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine 
• 16042-26-5 1-(phenylmethyl)-1H-imidazole-2-carboxylic acid 
• 53798-70-2 1-(1-benzyl-1H-imidazol-2-yl)-3-[1,3]dioxolan-2-yl-propan-1-ol 

Relevant articles and documents

Synthesis and electrochemical evaluation of 2-substituted imidazolium salts

Herein, we report the synthesis, electrochemical, and computational evaluation of six 2-substituted imidazolium bromides and six 2-substituted imidazolium triflates. All final compounds were obtained in 2 or fewer synthetic steps from inexpensive starting

Selection of chiral zinc catalysts for the kinetic resolution of esters via dynamic templating

Dynamic combinatorial libraries of chiral tetradentate bis-imine zinc(II) complexes have been prepared and screened for (1) their discrimination of enantiomeric picolinate esters and pyridyl phosphonate transition state analogs (TSAs) and (2) their cataly

Synthesis and biological evaluation of novel 2-(2-arylmethylene)hydrazinyl- 4-aminoquinazoline derivatives as potent antitumor agents

Two series of novel 2-(2-arylmethylene)hydrazinyl-4-aminoquinazoline derivatives were synthesized and evaluated for their cytotoxicity against H-460, HT-29, HepG2 and SGC-7901 cancer cell lines in vitro. Most compounds displayed moderate to excellent activity, with IC50 values ranging from 0.015 to 4.09 μM against all tested cell lines, respectively. The most promising compound 9p (E)-2-(2-((1-(2,3-dichlorobenzyl)-1H-imidazol-2-yl)methylene) hydrazinyl)-N-(1-methylpiperidin-4-yl)quinazolin-4-amine with IC50 values of 0.031 μM, 0.015 μM, 0.53 μM and 0.58 μM, which was 4- to 224 times more active than references 10 and Iressa, had emerged as a lead for further structural modifications.