1004517-67-2

Upstream product

• 626-62-0 Cyclohexyl iodide 
• 100-52-7 benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 780-21-2 N-(4-chlorobenzylidene)aniline 
• 108-94-1 cyclohexanone 
• 110-82-7 cyclohexane 

Relevant academic research and scientific papers

PEG 1000-based dicationic acidic ionic liquid as an efficient catalyst for mannich-type reaction in water

GRAPHICAL ABSTRACT PEG1000-based dicationic acidic ionic liquid (PEG1000-DAIL) was found to be an efficient and recyclable catalyst for Mannich-type reaction of different ketones with various aromatic aldehydes and aromatic amines in water to give various β-arylamino ketones in good yields. The catalytic system could be easily recovered and reused for at least six runs only with slight decrease in its activity.

Multicomponent Synthesis of α-Branched Tertiary and Secondary Amines by Photocatalytic Hydrogen Atom Transfer Strategy

A multicomponent carbonyl alkylative amination reaction is described. A variety of N-arylamines, aldehydes, and hydrocarbons have been examined as reaction substrates using tetrabutylammonium decatungstate as photocatalyst, providing the corresponding α-branched tertiary and secondary amines in good to moderate yields. The reaction proceeds through the generation of alkyl radicals by a light-promoted hydrogen atom transfer process followed by free radical addition to iminium ions generated in situ.

Efficient one-pot alkylation of imines using nanosilver iodide in aqueous media

An efficient ecofriendly method for the alkylation reaction of various imines is described by a simple one-pot reaction of aldehydes, amines and alkyl iodides in the presence of AgI nanoparticles in aqueous media. Silver iodide nanoparticles mediated an e

Indium-silver- and zinc-silver-mediated barbier-grignard-type alkylation reactions of imines by using unactivated alkyl halides in aqueous media

In the presence of In or Zn/AgI/InCl3, an efficient and practical method for the Barbier-Grignard-type alkylation reactions of simple imines by using a one-pot condensation of various aldehydes, amines (including the aliphatic and chiral version), and secondary alkyl iodides has been developed. The reaction proceeded more efficiently in water than in organic solvents. Without the use of CuI, it mainly gave the imine self-reductive coupling product, which was not the alkylated product. Good diastereoselectivities (up to 92:8 dr) were obtained when L-valine methyl ester was used as the substrate.

Indium - Copper-mediated barbier - Grignard-type alkylation reaction of imines in aqueous media

An efficient system of In/Cul/InCl3 was developed for Barbier-Grignard-type alkylation reactions of simple imines, using a one-pot condensation of various aldehydes, amines (including aliphatic and chiral version), and alkyl iodides in water or