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6-Chloro-5-fluoro-2-oxindole is a heterocyclic organic compound characterized by the presence of chloro, fluoro, and oxindole functional groups. It is widely recognized for its potential applications in the synthesis of pharmaceuticals and agrochemicals, as well as its demonstrated antimicrobial and anticancer activities, which have garnered significant interest in the field of medicinal chemistry research. Furthermore, its versatile reactivity and ability to participate in various chemical reactions make it a valuable reagent in organic synthesis. 6-Chloro-5-fluoro-2-oxindole is poised to contribute to a diverse array of applications within the realms of medicine and chemistry.

100487-74-9

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100487-74-9 Usage

Uses

Used in Pharmaceutical Synthesis:
6-Chloro-5-fluoro-2-oxindole is utilized as a key intermediate in the synthesis of various pharmaceuticals, owing to its unique structural features and reactivity. Its incorporation into drug molecules can potentially enhance their therapeutic properties and efficacy.
Used in Agrochemical Development:
In the agrochemical industry, 6-Chloro-5-fluoro-2-oxindole is employed as a building block for the creation of novel compounds with pesticidal or herbicidal properties. Its introduction into these molecules can lead to the development of more effective and environmentally friendly agrochemicals.
Used in Antimicrobial Applications:
6-Chloro-5-fluoro-2-oxindole has shown promise as an antimicrobial agent, making it a candidate for use in the development of new antibiotics or antifungal agents. Its ability to combat resistant strains of bacteria and fungi could contribute to addressing the growing issue of antimicrobial resistance.
Used in Anticancer Research:
As a compound with potential anticancer activities, 6-Chloro-5-fluoro-2-oxindole is used in medicinal chemistry research to explore its effects on various types of cancer cells. Its incorporation into anticancer drugs could lead to the development of novel therapeutic agents with improved efficacy and reduced side effects.
Used in Organic Synthesis as a Reagent:
Due to its versatile reactivity, 6-Chloro-5-fluoro-2-oxindole is employed as a reagent in organic synthesis, enabling chemists to carry out a range of chemical reactions. Its use in this capacity can facilitate the synthesis of complex organic molecules and contribute to the advancement of chemical research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 100487-74-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,8 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 100487-74:
(8*1)+(7*0)+(6*0)+(5*4)+(4*8)+(3*7)+(2*7)+(1*4)=99
99 % 10 = 9
So 100487-74-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClFNO/c9-5-3-7-4(1-6(5)10)2-8(12)11-7/h1,3H,2H2,(H,11,12)

100487-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-Chloro-5-fluoroindolin-2-one

1.2 Other means of identification

Product number -
Other names 6-chloro-5-fluoro-1,3-dihydroindol-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:100487-74-9 SDS

100487-74-9Relevant academic research and scientific papers

Intermediates for 5-fluoro-6-chlorooxindole

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, (2008/06/13)

Process for the production of 5-fluoro-6-chlorooxindole, (III), which is useful in the synthesis of certain analgesic and antiinflammatory agents, via two different synthetic pathways. Compounds of formula (I) and (II) shown below STR1 which are intermedi

1,3-dicarboxamide-oxindoles as antiinflammatory agents

-

, (2008/06/13)

1,3-Dicarboxamidooxindoles as antiinflammatory agents prepared by reaction of the 1-carbamoyloxindole with an isocyanate or by aminolysis of the corresponding alkyl 1-carbamoyloxindole-3-carboxylate.

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