100491-63-2 Usage
Uses
Used in Pharmaceutical Research:
1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, ethyl ester is used as a potential drug candidate for treating a range of medical conditions due to its ability to interact with various enzymes and proteins. Its unique chemical structure and properties make it a valuable compound for further investigation in drug discovery and development.
Used in Antimicrobial Therapy:
In the field of antimicrobial therapy, 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, ethyl ester is used as an antimicrobial agent to target and inhibit the activity of specific enzymes or proteins in bacteria or other microorganisms. Its ability to disrupt essential biological processes in these organisms can lead to their inhibition or destruction, making it a potential treatment option for various infections.
Used in Antitumor Therapy:
1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, ethyl ester is also used as an antitumor agent in cancer research. Its potential to inhibit the activity of enzymes or proteins involved in tumor growth and progression makes it a candidate for further investigation in the development of novel cancer therapies. 1,8-Naphthyridine-3-carboxylic acid,
1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-
oxo-, ethyl ester's ethyl ester form may enhance its solubility and bioavailability, allowing for improved delivery to tumor cells and increased therapeutic effects.
Used in Drug Delivery Systems:
To overcome potential limitations in the delivery and bioavailability of 1,8-Naphthyridine-3-carboxylic acid, 1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, ethyl ester, researchers may develop innovative drug delivery systems. These systems could include encapsulation in nanoparticles or other carriers, which can improve the compound's stability, solubility, and targeted delivery to specific cells or tissues, ultimately enhancing its therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 100491-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,9 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100491-63:
(8*1)+(7*0)+(6*0)+(5*4)+(4*9)+(3*1)+(2*6)+(1*3)=82
82 % 10 = 2
So 100491-63-2 is a valid CAS Registry Number.
100491-63-2Relevant academic research and scientific papers
Synthesis and Structure-Activity Relationships of New Arylfluoronaphthyridine Antibacterial Agents
Chu, Daniel T. W.,Fernandes, Prabhavathi B.,Claiborne, Akiyo K.,Gracey, Eugene H.,Pernet, Andre G.
, p. 2364 - 2369 (2007/10/02)
Novel arylfluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid have been prepared and their antibacterial activity evaluated.These derivatives are characterized by having a fluorine atom at 6-position, substituted amino groups at the 7-position, and substituted phenyl groups at the 1-position.The in vitro antibacterial potency is greatest when the 1-substituent is either p-fluorophenyl or o,p-difluorophenyl and the 7-substituent is a 3-amino-1-pyrrolidinyl group. 1-(2,4-Difluorophenyl)-6-fluoro-7-(3-amino-1-pyrrolidinyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (38) was found to possess excellent in vitro potency and in vivo efficacy.
