100491-97-2 Usage
Molecular structure
1,8-Naphthyridine-3-carboxylic acid, 7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-, ethyl ester has a complex structure that includes a naphthyridine core, a carboxylic acid group, a fluorine-substituted phenyl group, an acetylamino-pyrrolidinyl group, and an ethyl ester group.
Chemical classification
1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester is an ethyl ester derivative of naphthyridine-3-carboxylic acid, which is a type of organic compound.
Molecular weight
The molecular weight of 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester is 460.43 g/mol.
Pharmacological properties
Naphthyridine derivatives, including 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester, are known for their antimicrobial and antiviral activities. However, the specific properties and uses of 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester would need to be further studied and researched.
Fluorine substitution
The presence of fluorine atoms in the phenyl group of 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester may contribute to its pharmacological properties, as fluorine substitution can influence the compound's binding affinity, metabolic stability, and lipophilicity.
Acetylamino-pyrrolidinyl group
The acetylamino-pyrrolidinyl group in 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester may contribute to its biological activity, as this functional group is found in various pharmaceutical drugs and can interact with biological targets.
Ethyl ester group
The ethyl ester group in 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester may affect its solubility, stability, and bioavailability, as esters are generally more lipophilic and can be more easily absorbed by cells.
Potential applications
Due to its naphthyridine core and various functional groups, 1,8-Naphthyridine-3-carboxylic acid,
7-[3-(acetylamino)-1-pyrrolidinyl]-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro
-4-oxo-, ethyl ester may have potential applications in the development of new antimicrobial and antiviral drugs. Further research and studies are needed to determine its specific properties and uses.
Check Digit Verification of cas no
The CAS Registry Mumber 100491-97-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,9 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 100491-97:
(8*1)+(7*0)+(6*0)+(5*4)+(4*9)+(3*1)+(2*9)+(1*7)=92
92 % 10 = 2
So 100491-97-2 is a valid CAS Registry Number.
100491-97-2Relevant academic research and scientific papers
Synthesis and Structure-Activity Relationships of New Arylfluoronaphthyridine Antibacterial Agents
Chu, Daniel T. W.,Fernandes, Prabhavathi B.,Claiborne, Akiyo K.,Gracey, Eugene H.,Pernet, Andre G.
, p. 2364 - 2369 (2007/10/02)
Novel arylfluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid have been prepared and their antibacterial activity evaluated.These derivatives are characterized by having a fluorine atom at 6-position, substituted amino groups at the 7-position, and substituted phenyl groups at the 1-position.The in vitro antibacterial potency is greatest when the 1-substituent is either p-fluorophenyl or o,p-difluorophenyl and the 7-substituent is a 3-amino-1-pyrrolidinyl group. 1-(2,4-Difluorophenyl)-6-fluoro-7-(3-amino-1-pyrrolidinyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (38) was found to possess excellent in vitro potency and in vivo efficacy.
