1005348-16-2Relevant academic research and scientific papers
Halocyclization of Unsaturated Guanidines Mediated by Koser's Reagent and Lithium Halides
Daniel, Marion,Blanchard, Florent,Nocquet-Thibault, Sophie,Cariou, Kevin,Dodd, Robert H.
, p. 10624 - 10633 (2015/11/18)
The synthesis of halogenated cyclic guanidines through iodine(III)-mediated umpolung of halide salts is described. Cyclic guanidines of various sizes can be obtained with generally excellent regioselectivities through either a chloro- or a bromocyclization, using Koser's reagent and the corresponding lithium salt.
Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines
Al Shuhaib, Zainab,Davies, Deiniol H.,Dennis, Mark,Evans, Daniel M.,Fletcher, Matthew D.,Franken, Herjan,Hancock, Paul,Hollinshead, Jackie,Jones, Iestyn,K?hm, Kristina,Murphy, Patrick J.,Nash, Robert,Potter, David,Rowles, Richard
, p. 4412 - 4419 (2014/06/10)
The cyclisation of mono-protected and bis-protected guanidines 8a-j under standard iodocyclisation conditions (I2/K2CO3) gave the guanidine heterocycles 9-25 via either a direct cyclisation or by a cyclisation/ring-contrac
Cyclisation reactions of bis-protected guanidines
Albrecht, Christiane,Barnes, Sarah,B?ckemeier, Henning,Davies, Deiniol,Dennis, Mark,Evans, Daniel M.,Fletcher, Matthew D.,Jones, Iestyn,Leitmann, Vera,Murphy, Patrick J.,Rowles, Richard,Nash, Robert,Stephenson, Richard A.,Horton, Peter N.,Hursthouse, Michael B.
, p. 185 - 188 (2008/03/30)
The cyclisation of N-allyl- and N-homoallylguanidines using DMDO or I2/K2CO2 leading to novel heterocycles is reported.
