26728-58-5

Usage

Uses

Used in Pharmaceutical Industry:
3-METHYL-2-BUTENE-1-AMINE HCL is used as a chemical intermediate for the synthesis of N9-substituted N6-[(3-methylbut-2-en-1-yl)amino]purine derivatives. These derivatives exhibit significant biological activity and are utilized in various cytokinin bioassays, which are essential for understanding the role of cytokinins in cell growth and development.
Used in Research and Development:
In the field of research and development, 3-METHYL-2-BUTENE-1-AMINE HCL serves as a key compound for the exploration of new drug candidates and the study of their interactions with biological systems. Its unique chemical structure allows for the development of novel therapeutic agents with potential applications in various medical conditions.
Used in Chemical Synthesis:
3-METHYL-2-BUTENE-1-AMINE HCL is also employed in the chemical synthesis of various compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its versatile reactivity and functional groups make it a valuable building block for the creation of complex molecular structures with specific properties and applications.

Upstream product

• 870-63-3 prenyl bromide 
• 1191-16-8 3-methylbut-2-enyl acetate 
• 15936-45-5 N-prenylphthalimide 
• 556-82-1 3-methyl-2-buten-1-ol 

Downstream Products

• 543-83-9 galegine 
• 1005348-16-2 C₂₂H₂₅N₃O₄ 
• 2365-40-4 N₆-(2-isopentenyl)adenine 
• 53274-45-6 2-Methylthio-trans-ribosylzeatin 
• 6025-53-2 trans-zeatin 9-β-D-ribofuranoside 
• 1005348-16-2 N-(3,3-dimethylallyl)-N'-N-bis-Cbz-guanidine 
• 55289-73-1 N-(3-methylbut-2-en-1-yl)-4-nitrobenzamide 
• 1365566-19-3 C₁₈H₂₄NO₅P 
• 1365566-35-3 C₁₈H₂₄NO₃P 
• 1365566-49-9 C₁₈H₂₄NO₃P 
• 1262675-44-4 benzyl (5-iodo-4,4-dimethyltetrahydropyrimidin-2(1H)-ylidene)carbamate 
• 1262675-51-3 C₁₄H₁₉N₃O₂ 
• 146269-39-8 (E)-Caracasanamide 
• 258850-23-6 (+/-)-ethyl N-(5-chloro-2-nitrobenzoyl)-N-(3-methyl-2-butenyl)alanine 

Relevant academic research and scientific papers

Highly Stereoselective Intermolecular Haloetherification and Haloesterification of Allyl Amides

An organocatalytic and highly regio-, diastereo-, and enantioselective intermolecular haloetherification and haloesterification reaction of allyl amides is reported. A variety of alkene substituents and substitution patterns are compatible with this chemistry. Notably, electronically unbiased alkene substrates exhibit exquisite regio- and diastereoselectivity for the title transformation. We also demonstrate that the same catalytic system can be used in both chlorination and bromination reactions of allyl amides with a variety of nucleophiles with little or no modification. A highly regioselective intermolecular haloetherification that proceeds with excellent enantioselectivity, catalyzed by cinchona alkaloid dimers, is reported. The regioselectivity is preserved for unbiased alkyl substituted allyl amides with either E or Z geometry. (DHQD)2PHAL=hydroquinidine 1,4-phthalazinediyl diether.

Benzylguanidines and other galegine analogues inducing weight loss in mice

Dimethylallylguanidine, also known as galegine, isolated from Galega officinalis, has been shown to have weight reducing properties in vivo. Substitution of the guanidine group with an N-cyano group and replacement of guanidine with amidine, pyrimidine, pyridine, or the imidazole moieties removed the weight reducing properties when evaluated in BALB/c mice. However, retention of the guanidine and replacement of the dimethylallyl group by a series of functionalized benzyl substituents was shown to exhibit, and in some cases significantly improve, the weight reducing properties of these molecules in BALB/c, ob/ob, and diet induced obesity (DIO) mice models. The lead compound identified, across all models, was 1-(4-chlorobenzyl)guanidine hemisulfate, which gave an average daily weight difference (% from time-matched controls; ± SEM) of -19.7 ± 1.0, -11.0 ± 0.7, and -7.3 ± 0.8 in BALB/c, ob/ob, and DIO models, respectively.

WEIGHT REDUCING COMPOUNDS

The present invention relates to compounds which find use as weight reducing agents, and find use in treating obesity and/or excess adiposity.

Heteroatom-bearing ligands and metal complexes thereof

Novel compounds containing a heteroatom-bearing bridge and novel complexes of these compounds with metals. The novel compounds and complexes are useful in diagnostic and therapeutic methods.

Synthesis of Amido-ureas and the Nature of Caracasanamide, the Hypotensive Principle of Verbesina caracasana

Syntheses of the (E)-1 and (Z)-2 forms of 1-(3-methylbut-2-enyl)-3-(4-butyl)urea, proposed structures for the natural hypotensive caracasanamide, have been carried out.The compounds were found not to be identical wit

PALLADIUM(0) CATALYZED AZIDATION AND AMINATION OF ALLYL ACETATES. SELECTIVE SYNTHESIS OF ALLYL AZIDES AND PRIMARY ALLYLAMINES

Palladium catalyzed reaction of allyl acetates with azide ion gives allyl azides, which are readily converted into the corresponding primary allylamines upon treatment with PPh3/NaOH.