1005500-94-6

Basic information

• Product Name: N-methyl-N-(p-tolylsulfonyl)phenylacetamide
• Synonyms: N-methyl-N-(p-tolylsulfonyl)phenylacetamide
• CAS NO: 1005500-94-6
• Molecular Weight: 303.382
• Mol File: 1005500-94-6.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: N-methyl-N-(p-tolylsulfonyl)phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(p-tolylsulfonyl)phenylacetamide(1005500-94-6)
• EPA Substance Registry System: N-methyl-N-(p-tolylsulfonyl)phenylacetamide(1005500-94-6)

Safety Data

• Hazardous Substances Data: 1005500-94-6(Hazardous Substances Data)

Upstream product

• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 1005500-77-5 N,4-dimethyl-N-(phenylethynyl)benzenesulfonamide 
• 132145-64-3 dimethyl 2-(p-methylphenyl)cyclopropane-1,1-dicarboxylate 
• 932-87-6 1-Bromo-2-phenylacetylene 
• 4076-36-2 5-methyltetrazole 
• 14678-02-5 5-amino-3-methylisoxazole 
• 62-53-3 aniline 
• 536-74-3 phenylacetylene 
• 1613-37-2 Quinoline N-oxide 
• 2150-46-1 Methyl 2,5-dihydroxybenzoate 
• 1005500-75-3 N-(methyl)-N-(p-toluenesulfonyl)ethynylamine 
• 98-80-6 phenylboronic acid 
• 64-04-0 phenethylamine 

Downstream Products

• 1445314-44-2 2-(N-methyl-N-tosylamino)-3-phenylpropionitrile 

Relevant articles and documents

Direct Hydroheteroarylation of Ynamides with 2H-Tetrazoles: Regio- and Stereoselective Synthesis of (Z)-α-Tetrazole Enamides

We herein report the direct reaction of ynamides with 2H-tetrazoles under metal-free conditions to provide a variety of functionalized (Z)-α-tetrazole enamide products in high yields, including the N-2 and N-1 adducts that are easily separated. The reacti

Synthesis of poly-functionalized benzofurans: Via one-pot domino oxidation/[3+2] cyclization reactions of a hydroquinone ester and ynamides

Densely substituted amino-functionalized benzofurans were concisely accessed via the first one-pot domino oxidation/[3+2] cyclization of a hydroquinone ester and easily accessible ynamides under mild conditions in a short time. The complex benzofurans wer

Reactivity of ynamides with AlCl3 and ICl: Ready access to (E)-α-chloroenamides and (E/Z)-α-chloro-β-iodo-enamides

Abstract: AlCl3 acts as a chlorinating agent for ynamides in the presence of stoichiometric amount of water in the environmentally benign solvent dimethylcarbonate, affording efficient access to (E)-α-chloroenamides via hydrochlorination, with water as a protic source. The role of water in the reaction was proven by deuterium labelling experiment. Epoxy-ynamides undergo iodochlorination in addition to the cleavage of the epoxy ring to afford (E/Z)-α-chloro-β-iodo-enamides. Regio- and stereochemical assignments for the products are based on X-ray crystallographic studies. Graphic abstract: Chloroenamides are formed regio- and stereo-specifically via hydrochlorination of ynamides with AlCl3+H2O (1:1) in a dimethyl carbonate; aryl substituted epoxy ynamides afford (iodo)(chloro) enamides upon treatment with ICl.[Figure not available: see fulltext.]

Metal-free C8-H functionalization of quinolineN-oxides with ynamides

The metal-free C8-H functionalization of quinolineN-oxides with ynamides is unveiled for the first time by the intramolecular Friedel-Crafts-type reaction of quinolyl enolonium intermediates generated from Br?nsted acid-catalyzed addition of quinolineN-ox

Facile one-pot synthesis of 2-aminoindoles from simple anilines and ynamides

A highly effective and straightforward one-pot synthesis of diversely substituted 2-aminoindoles has been developed, involving sequential Au(i)-catalyzed regioselective hydroamination and CuCl2-mediated oxidative cyclization. This protocol offers an operationally easy, simple, robust, and sustainable approach with the use of readily available starting materials, good functional group tolerance, and high practicality and efficiency. This journal is