1006030-90-5Relevant articles and documents
2-O-Alkylated para-benzamide α-helix mimetics: The role of scaffold curvature
Azzarito, Valeria,Prabhakaran, Panchami,Bartlett, Alice I.,Murphy, Natasha S.,Hardie, Michaele J.,Kilner, Colin A.,Edwards, Thomas A.,Warriner, Stuart L.,Wilson, Andrew J.
, p. 6469 - 6472 (2012/09/08)
The design and synthesis of a new 2-O-alklyated benzamide α-helix mimetic is described. Comparison with regioisomeric 3-O-alkylated benzamides permits a preliminary evaluation of the role that mimetic curvature has in determining molecular recognition properties.
Synthesis of functionalised aromatic oligamide rods
Plante, Jeffrey,Campbell, Fred,Malkova, Barbora,Kilner, Colin,Warriner, Stuart L.,Wilson, Andrew J.
, p. 138 - 146 (2008/09/20)
A current goal in synthetic chemistry is the design and synthesis of molecules that adopt well defined conformations - so called foldamers. In this manuscript we describe a modular approach for construction of rod shaped para-oligobenzamide molecules. Our approach permits regiospecific incorporation of side chains through a phenolic ether linkage on the scaffold; a feature that partly restricts the conformation of the rod through intramolecular hydrogen-bonding. The Royal Society of Chemistry 2008.