681465-85-0

Basic information

• Product Name: Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI)
• Synonyms: Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI);Methyl 4-amino-3-isopropoxybenzoate
• CAS NO: 681465-85-0
• Molecular Formula: C₁₁H₁₅NO₃
• Molecular Weight: 209.2417
• Product Categories: AMINOACID
• Mol File: 681465-85-0.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI)(681465-85-0)
• EPA Substance Registry System: Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI)(681465-85-0)

Safety Data

• Hazardous Substances Data: 681465-85-0(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI) is a chemical compound with the molecular formula C11H17NO2. It is a methyl ester of benzoic acid and is also known as methyl 4-amino-3-(1-methylethoxy)benzoate. Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI) is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has potential applications in the field of medicine and agriculture due to its unique chemical structure. However, it is important to handle this chemical with care, as it may have harmful effects if not used properly. Overall, Benzoic acid, 4-amino-3-(1-methylethoxy)-, methyl ester (9CI) is a versatile compound with potential uses in various industries.

Upstream product

• 63435-16-5 3-hydroxy-4-aminobenzoic acid methyl ester 
• 75-26-3 isopropyl bromide 
• 619-14-7 3-hydroxy-4-nitro-benzoic acid 
• 713-52-0 methyl 3-hydroxy-4-nitrobenzoate 
• 159783-41-2 methyl 3-isopropyloxy-4-nitrobenzoate 
• 75-30-9 2-iodo-propane 

Downstream Products

• 1006030-90-5 methyl 3-isopropoxy-4-(3-(2-naphthylmethoxy)-4-nitro-benzoylamino)-benzoate 
• 1006030-86-9 methyl 3-isopropoxy-4-(3-benzyloxy-4-nitro-benzoylamino)-benzoate 
• 1006030-84-7 methyl 3-isopropoxy-4-(3-propoxy-4-nitro-benzoylamino)-benzoate 
• 1006030-83-6 methyl 3-isopropoxy-4-(3-isopropoxy-4-nitro-benzoylamino)-benzoate 
• 1318208-92-2 isopropyl 3-isopropoxy-4-(3-isopropoxy-4-nitrobenzamido)benzoate 
• 1373319-37-9 methyl 3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzoate 
• 1006030-92-7 methyl 3-isopropoxy-4-(3-isopropoxy-4-amino-benzoylamino)-benzoate 
• 1006031-13-5 methyl 3-isopropoxy-4-(3-isopropoxy-4-(3-isopropoxy-4-nitro-benzoylamino)-benzoylamino)-benzoate 
• 1006031-03-3 methyl 3-isopropoxy-4-(3-isopropoxy-4-(3-isopropoxy-4-amino-benzoylamino)-benzoylamino)-benzoate 
• 1190360-14-5 3-isopropoxy-4-(3-isopropoxy-4-(3-isopropoxy-4-amino-benzoylamido)-benzoylamido)-benzoic acid 
• 1373319-41-5 methyl 3-isopropoxy-4-(3-isopropoxy-4-(6-isopropoxy-5-nitropicolinamido)benzamido)benzoate 
• 1373319-42-6 methyl 3-isopropoxy-4-(6-isopropoxy-5-(6-isopropoxy-5-nitropicolinamido)picolinamido)benzoate 
• 1373319-43-7 methyl 3-isopropoxy-4-(6-isopropoxy-5-(3-isopropoxy-4-nitrobenzamido)picolinamido)benzoate 
• 1373319-39-1 methyl 4-(5-amino-6-isopropoxypicolinamido)-3-isopropoxybenzoate 

Relevant articles and documents

ANTIVIRAL HETEROCYCLIC COMPOUNDS

The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit Human Respiratory Syncytial Virus (HRSV) or Human Metapneumovirus (HMPV) inhibitors. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HRSV or HMPV infection. The invention also relates to methods of treating an HRSV or HMPV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

The Albicidin Resistance Factor AlbD Is a Serine Endopeptidase That Hydrolyzes Unusual Oligoaromatic-Type Peptides

The para-aminobenzoic acid-containing peptide albicidin is a pathogenicity factor synthesized by Xanthomonas albilineans in infections of sugar cane. Albicidin is a nanomolar inhibitor of the bacterial DNA gyrase with a strong activity against various Gram-negative bacteria. The bacterium Pantoea dispersa expresses the hydrolase AlbD, conferring natural resistance against albicidin. We show that AlbD is a novel type of endopeptidase that catalyzes the cleavage of albicidin at a peptide backbone amide bond, thus abolishing its antimicrobial activity. Additionally, we determined the minimal cleavage motif of AlbD with substrates derived by chemical synthesis. Our results clearly identify AlbD as a unique endopeptidase that is the first member of a new subfamily of peptidases. Our findings provide the molecular basis for a natural detoxification mechanism, potentially rendering a new tool in biological chemistry approaches.

Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: Identification of potent Bcl-xL inhibitors

By conducting a structure-activity relationship study of the backbone of a series of oligoamide-foldamer-based α-helix mimetics of the Bak BH3 helix, we have identified especially potent inhibitors of Bcl-xL. The most potent compound has a Ki value of 94 nM in vitro, and single-digit micromolar IC50 values against the proliferation of several Bcl-xL-overexpressing cancer cell lines. The Royal Society of Chemistry 2012.