100608-93-3Relevant academic research and scientific papers
Palladium-catalyzed decarboxylative: Ortho-amidation of O-methyl ketoximes with oxamic acids
Jing, Kun,Cui, Peng-Cheng,Wang, Guan-Wu
, p. 12551 - 12554 (2019)
The first palladium-catalyzed ortho-amidation of ketoximes has been developed with readily available, easy to handle and environment-friendly N,N-disubstituted oxamic acids as the amidation sources. When N-monosubstituted oxamic acids are used as the substrates, the formed ortho-amidated ketoximes undergo further intramolecular cyclization to provide 3-methyleneisoindolinones.
α-Zinc O-vinyl carbamates as anionic Friedel-Crafts equivalents. Cross coupling reactions with aryl and heteroaryl halides and triflates
Superchi, Stefano,Sotomayor, Nuria,Miao, Guobin,Joseph, Babu,Snieckus, Victor
, p. 6057 - 6060 (2007/10/03)
A mild, efficient, and general Negishi cross coupling protocol, 4 + 5 → 6 is reported; the hydrolysis of products 6 to acetophenones demonstrates the anionic Friedel-Crafts equivalency of the overall synthetic operation.
