15754-20-8

Basic information

• Product Name: Ethanone, 1-phenyl-, O-methyloxime, (E)-
• CAS NO: 15754-20-8
• Molecular Formula: C9H11NO
• Molecular Weight: 149.192
• Mol File: 15754-20-8.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-phenyl-, O-methyloxime, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-phenyl-, O-methyloxime, (E)-(15754-20-8)
• EPA Substance Registry System: Ethanone, 1-phenyl-, O-methyloxime, (E)-(15754-20-8)

Safety Data

• Hazardous Substances Data: 15754-20-8(Hazardous Substances Data)

Upstream product

• 593-56-6 N-methoxylamine hydrochloride 
• 98-86-2 acetophenone 
• 14221-01-3 tetrakis(triphenylphosphine) palladium⁽⁰⁾ 
• 201230-82-2 carbon monoxide 
• 142533-52-6 (Z)-2-bromo-1-phenylethanone O-methyl oxime 
• 77561-95-6 (Z)-2-chloro-1-phenylethanone O-methyl oxime 
• 70-11-1 α-bromoacetophenone 
• 98-80-6 phenylboronic acid 
• 532-27-4 1-chloroacetophenone 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 74-88-4 methyl iodide 
• 10341-75-0 (E)-1-phenylethanone oxime 
• 67-62-9 O-Methylhydroxylamin 
• 2181-42-2 trimethylsulphonium iodide 

Downstream Products

• 2627-86-3 (S)-1-phenyl-ethylamine 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 135923-85-2 O-Methyl-N-((S)-1-phenyl-ethyl)-hydroxylamine 
• 135879-69-5 (R)-O-methyl-N-(α-methylbenzyl)hydroxylamine 
• 618-36-0 rac-methylbenzylamine 
• 72278-09-2 (E)-1-(3-mitrophenyl)ethan-1-one O-methyl oxime 
• 281681-21-8 3-[(4S,5S)-4,5-Bis(1-methoxycyclopentyl)-1,3,2-dioxoborolan-2-yl]propiophenone O-methyloxime 

Relevant articles and documents

Synthesis of 14C-labeled S-(-)-1-phenylethylamine and its application to the synthesis of [14C] CI-1021, a potential antiemetic agent(1)

S-(-)-1-[U-ring- 14C]phenylethylamine 3 was synthesized through the enantioselective borane reduction of E-[U-ring-14C]acetophenone oxime methyl ether derived from [U-ring-14C]acetophenone. The overall radiochemical yield was 66.7%. The enantiomeric excess (ee) was 96.60%. Coupling the labeled amine 3 with (R)-N-[(benzo[b]furan-2-ylmethoxy)-carbonyl-2-methyltryptophan 4 provided [R-(R* , S*)] {1-(1H-indole-3-ylmethyl)-1-methyl-2-oxo-2-[(1-[U-ring-14C]phenylethyl) amino]ethyl} carbamic acid benzo[b]furan-2-ylmethyl ester (CI-1021), a potential antiemetic agent.

Rh-Catalyzed N-O Bond Cleavage of Anthranil: A C-H Amination Reagent for Simultaneous Incorporation of Amine and a Functional Group

A novel Rh(III)-catalyzed C-H bond amination with the simultaneous release of a formyl group at distal positions is realized employing anthranil as a new type of C-H amination reagent. This chemistry provides an efficient protocol for the synthesis of 2-a

Use of Strain-Release for the Diastereoselective Construction of Quaternary Carbon Centers

Herein, we describe the formation of quaternary carbon centers with excellent diastereoselectivity via a strain-release protocol. An organometallic species is generated by Cp*Rh(III)-catalyzed C-H activation, which is then coupled with strained bicyclobut

Palladium-catalyzed C-H activation/C-C cross-coupling reactions: Via electrochemistry

Palladium-catalyzed C-H activation/C-C cross-coupling reactions typically require stoichiometric chemical oxidants and exogenous ligands. However, there are significant disadvantages associated with the use of traditional stoichiometric oxidants. To overcome these issues, we have developed an electrochemical strategy to achieve methylation and acylation.