100645-44-1

Upstream product

• 100-02-7 4-nitro-phenol 
• 5531-53-3 1,2,3,5,6-penta-O-acetyl-α,β-D-galactofuranose 
• 10257-28-0 D-Galactose 
• 108-24-7 acetic anhydride 
• 59-23-4 D-Galactose 
• 223412-29-1 Acetic acid (2S,3S,4R)-4-acetoxy-2-((R)-1,2-diacetoxy-ethyl)-5-octyloxy-tetrahydro-furan-3-yl ester 
• 202403-49-4 n-octyl D-galactofuranoside 

Downstream Products

• 100645-45-2 (4-nitro)phenyl β-D-galactofuranoside 

Relevant academic research and scientific papers

Identification and characterization of a novel galactofuranose-specific β-D-galactofuranosidase from Streptomyces species

β-D-galactofuranose (Galf) is a component of polysaccharides and glycoconjugates and its transferase has been well analyzed. However, no β-D-galactofuranosidase (Galf-ase) gene has been identified in any organism. To search for a Galf-ase gene we screened

An original chemoenzymatic route for the synthesis of β-D- galactofuranosides using an α-l-arabinofuranosidase

Galactofuranose is a widespread component of cell wall polysaccharides in bacteria, protozoa and fungi, but is totally absent in mammals. Importantly, galactofuranose is a key constituent of major cell envelope polysaccharides in pathogenic mycobacteria.

Chemo-enzymatic synthesis of p-nitrophenyl β-D-galactofuranosyl disaccharides from Aspergillus sp. fungal-type galactomannan

β-D-Galactofuranose (Galf) is a component of polysaccharides and glycoconjugates. There are few reports about the involvement of galactofuranosyltransferases and galactofuranosidases (Galf-ases) in the synthesis and degradation of galactofuranose-containing glycans. The cell walls of filamentous fungi in the genus Aspergillus include galactofuranose-containing polysaccharides and glycoconjugates, such as O-glycans, N-glycans, and fungal-type galactomannan, which are important for cell wall integrity. In this study, we investigated the synthesis of p-nitrophenyl β-D-galactofuranoside and its disaccharides by chemo-enzymatic methods including use of galactosidase. The key step was selective removal of the concomitant pyranoside by enzymatic hydrolysis to purify p-nitrophenyl β-D-galactofuranoside, a promising substrate for β-D-galactofuranosidase from Streptomyces species.