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N-(4-iodophenyl)-N-methylnitrous amide, also known as methyl iodobenzene nitrone, is a chemical compound with the molecular formula C8H8IN3O. It is a derivative of nitrous amide, featuring a 4-iodophenyl group attached to the nitrogen atom. N-(4-iodophenyl)-N-methylnitrous amide is often used as a spin trapping agent in electron paramagnetic resonance (EPR) spectroscopy to study free radicals and reactive oxygen species in biological systems. Its unique structure allows it to react with radicals, forming stable nitroxide radicals that can be detected and analyzed. Due to its reactivity and applications in studying radical chemistry, N-(4-iodophenyl)-N-methylnitrous amide is an important tool in the field of chemical biology and medicinal chemistry.

1007-20-1

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1007-20-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1007-20-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1007-20:
(6*1)+(5*0)+(4*0)+(3*7)+(2*2)+(1*0)=31
31 % 10 = 1
So 1007-20-1 is a valid CAS Registry Number.

1007-20-1Downstream Products

1007-20-1Relevant academic research and scientific papers

Rh(III)-catalyzed N-nitroso-directed C-H olefination polymerization

Liu, Zhongsu,Zeng, Hua,Zhang, Wenjing,Song, Chao,Yang, Fan,Liu, Yun,Zhu, Jin

, p. 152 - 159 (2019)

Transition metal-catalyzed directed C-H functionalization promises a straightforward route to polymerization but remains highly underexplored. We report herein the development of a polymer synthesis protocol based on Rh(III)-catalyzed N-nitroso-directed C-H olefination reaction. The single bifunctional monomer approach allows the high-yield generation of polymers with relatively narrow PDI under mild conditions. Further convenient denitrosation transformation furnishes responsive fluorescent polymers with metal ion-selective quenching behaviors. The high Hg2+ selectivity observed in one system provides a handy enabling tool for detecting this hazardous species.

Highly selective sp3 C-N bond activation of tertiary anilines modulated by steric and thermodynamic factors

Jia, Xiaodong,Li, Pengfei,Shao, Yu,Yuan, Yu,Ji, Honghe,Hou, Wentao,Liu, Xiaofei,Zhang, Xuewen

supporting information, p. 5568 - 5574 (2017/12/06)

A highly selective sp3 C-N cleavage of tertiary anilines was achieved using the TBN/TEMPO catalyst system. When N,N-diaklylanilines (alkyl, benzyl) were employed, the N-CH3 bond was selectively cleaved via radical C-H activation. Moreover, when the allyl group was installed, totally reverse selectivity was observed. It is worth noting that the solvent effect is also crucial to obtain high reaction efficiency and selectivity.

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