1007-80-3

Basic information

• Product Name: 2-ethoxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide
• CAS NO: 1007-80-3
• Molecular Formula: C₇H₁₅O₄P
• Molecular Weight: 194.1654
• Mol File: 1007-80-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 220.2°C at 760 mmHg
• Flash Point: 101.2°C
• Density: 1.13g/cm³
• Vapor Pressure: 0.17mmHg at 25°C
• Refractive Index: 1.431
• CAS DataBase Reference: 2-ethoxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethoxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide(1007-80-3)
• EPA Substance Registry System: 2-ethoxy-5,5-dimethyl-1,3,2-dioxaphosphinane 2-oxide(1007-80-3)

Safety Data

• Hazardous Substances Data: 1007-80-3(Hazardous Substances Data)

Upstream product

• 116402-41-6 1,3-bis-diethoxyphosphoryloxy-2,2-dimethyl-propane 
• 4090-55-5 2-chloro-5,5-dimethyl[1,3,2]dioxaphosphinane 2-oxide 
• 141-52-6 sodium ethanolate 
• 64-17-5 ethanol 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 1007-57-4 2-ethoxy-5,5-dimethyl-1,3,2-dioxaphosphorinane 
• 62217-81-6 5,5-dimethyl-2-(2,2,2-trichloro-ethoxy)-[1,3,2]dioxaphosphinane 2-oxide 
• 1498-51-7 ethyl phosphodichloridite 

Relevant articles and documents

Rate and product studies in the solvolyses of two cyclic phosphorochloridate esters

Kinetic and product studies of the solvolyses of acyclic phosphorochloridates are extended to two cyclic diesters, 2-chloro-1,3,2- dioxaphospholane-2-oxide (1) and 2-chloro-5,5-dimethyl-1,3,2-dioxaphosphorinane- 2-oxide (2). Slightly faster solvolyses are observed for 1 than for the acyclic dimethyl phosphorochloridate (3), and 2 solvolyzes somewhat slower than 3. An extended Grunwald-Winstein equation treatment shows similar sensitivities to changes in solvent nucleophilicity and solvent ionizing power for 1, 2, and 3, and a concerted SN2 attack is proposed in each case. Product studies for the solvolyses of 2 in aqueous alcohols are presented. [image presented]. Copyright Taylor & Francis Group, LLC.

2-Alkyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-ones α-Lithiated Carbanions. Synthesis, Stability, and Conformation

The preparation and a conformational study of lithiated 2-alkyl-5,5-dimethyl-1,3,2-dioxaphosphorinan-2-ones (2) in THF-hexane are described.These anions are present as two rapidly interconverting species with the P=O bond either axial (2a) or equatorial (2e).They are thermally unstable, but can be stabilised by the presence of one equivalent of LiBr or of lithium di-isopropylamide.A 31P NMR study of the self condensation of the carbanions (2) showed that the phosphorus atom in the axial conformation (2a) is more electrophilic than in the equatorial one (2e).An X-ray structural study of 2,5,5-trimethyl-1,3,2-dioxaphosphorinan-2-one is described.