100716-41-4Relevant academic research and scientific papers
Novel benzo[d]imidazole-2(3H)-thiones as potent inhibitors of the α-melanocyte stimulating hormone induced melanogenesis in melanoma B16 cells
Lee, Jee-Hyun,Thanigaimalai, Pillaiyar,Lee, Ki-Cheul,Bang, Seong-Cheol,Kim, Min-Seok,Sharma, Vinay Kumar,Yun, Cheong-Yong,Roh, Eunmiri,Kim, Youngsoo,Jung, Sang-Hun
experimental part, p. 918 - 921 (2010/09/04)
In order to determine the optimum size of heterocycle of lead compound 1 (6-methyl-3-phenethyl-3,4-dihydro-1H-quinoline-2-thione; IC50=0.8 μM) for inhibition of melanogenesis, we have synthesized and evaluated some benzimdazole-2(3H)-thiones 5a
Specific features of nucleophilic substitution in 1-chloro-3,4- dinitrobenzene
Zotova,Kushakova,Kuznetsov,Rodin,Garabadzhiu
, p. 1473 - 1476 (2007/10/03)
Effects of the solvent, temperature, and nucleophile nature on the selectivity of nucleophilic substitution in 1-chloro-3,4-dinitrobenzene were studied, and optimal conditions were found for the synthesis and isolation of particular products.
