1007313-85-0Relevant academic research and scientific papers
Synthesis of pochoxime prodrugs as potent HSP90 inhibitors
Wang, Cuihua,Barluenga, Sofia,Koripelly, Girish K.,Fontaine, Jean-Gonzague,Chen, Ruihong,Yu, Jin-Chen,Shen, Xiaodong,Chabala, John C.,Heck, James V.,Rubenstein, Allan,Winssinger, Nicolas
supporting information; experimental part, p. 3836 - 3840 (2010/04/05)
Pochoximes are potent inhibitors of heat shock protein 90 (HSP90) based on the radicicol pharmacophores. Herein we present a pharmacokinetics and pharmacodynamics evaluation of this compound series as well as a phosphate prodrug strategy to facilitate for
