100826-98-0 Usage
Uses
Used in Pharmaceutical Industry:
4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-2-propanoic Acid is used as an intermediate in the preparation of platelet-activating factor (PAF) antagonists. PAF antagonists are important in the development of drugs targeting various inflammatory and cardiovascular conditions, as they can help regulate the activity of platelets and reduce the risk of clot formation.
As an intermediate, 4-(2-Chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-2-propanoic Acid plays a crucial role in the synthesis of PAF antagonists, contributing to the development of effective therapeutic agents for treating a range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 100826-98-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,2 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 100826-98:
(8*1)+(7*0)+(6*0)+(5*8)+(4*2)+(3*6)+(2*9)+(1*8)=100
100 % 10 = 0
So 100826-98-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H15ClN4O2S/c1-10-21-22-15-9-20-17(12-4-2-3-5-14(12)19)13-8-11(6-7-16(24)25)26-18(13)23(10)15/h2-5,8H,6-7,9H2,1H3,(H,24,25)
100826-98-0Relevant academic research and scientific papers
Brotizolam radioimmunoassay: Development, evaluation, and application to human plasma samples
Bechtel,Weber
, p. 1265 - 1269 (2007/10/02)
A radioimmunoassay for the determination of the hypnotic agent brotizolam (11) was developed. With this procedure, an antiserum was used which was obtained from rabbits immunized with the hapten 10 (We 934) covalently bound to serum albumin and tritium-la