100847-13-0Relevant academic research and scientific papers
Synthese d'acetals cycliques dans des conditions douces; Applications a l'acetalisation du chloramphenicol
Meslard, J. C.,Subira, F.,Vairon, J. P.,Guy, A.,Garreau, R.
, p. 84 - 89 (2007/10/02)
Acetalization of 1-2 and 1-3 diols, even as sterically crowded as chloramphenicol, by carbonyl derivatives with substituents of various sizes has been performed at room temperature under mild conditions, by using heterogeneous catalysis (sulfonated polystyrene) in the presence of molecular sieves.Several new acetals of chloramphenicol have thus been obtained in good yields, isolated and characterized.
