100865-29-0

Basic information

• Product Name: 5-methoxy-2-(4-chlorophenyl)-1H-indole
• Synonyms: 5-methoxy-2-(4-chlorophenyl)-1H-indole
• CAS NO: 100865-29-0
• Molecular Weight: 257.719
• Mol File: 100865-29-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 5-methoxy-2-(4-chlorophenyl)-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-2-(4-chlorophenyl)-1H-indole(100865-29-0)
• EPA Substance Registry System: 5-methoxy-2-(4-chlorophenyl)-1H-indole(100865-29-0)

Safety Data

• Hazardous Substances Data: 100865-29-0(Hazardous Substances Data)

Upstream product

• 1126-46-1 Methyl 4-chlorobenzoate 
• 117616-04-3 4-methoxy-2-trimethylsilylmethylbenzanilide 
• 1006-94-6 5-methoxylindole 
• 637-87-6 1-Chloro-4-iodobenzene 

Relevant articles and documents

PROCESSES FOR PREPARING INDOLES

Methods for the synthesis of an indole in provided. Methods comprise oxidizing a N-aryl imine in the presence of a palladium-based catalyst, an oxidant, and a solvent.

Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: Indole synthesis from anilines and ketones

We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant. The process allows quick and atom-economical assembly of indole rings from inexpensive and readily available anilines and ketones and tolerates a broad range of functional groups.