100866-04-4Relevant articles and documents
A new efficient synthetic method for 3-iodothyronamine and its potent hypothermic efficacy
Kim, Joong-Gon,Song, Young-Kyu,Jeon, Su-Yeon,Lim, Ye-Ji,Ju, Hyunwoo,Choi, Inho,Chung, Chan-Moon
, p. 2205 - 2208 (2012/04/04)
We developed a new efficient synthetic method for a 3-iodothyronamine (T1AM) that has advantages of less synthetic steps and much higher overall yield compared to those in the conventional method. Our animal study showed that T1AM synthesized by the method exerted a potent hypothermic effect in non-hibernator mice.