1009-01-4

Basic information

• Product Name: Methanesulfonic acid 2-methylphenyl ester
• Synonyms: Methanesulfonic acid 2-methylphenyl ester
• CAS NO: 1009-01-4
• Molecular Formula: C₈H₁₀O₃S
• Molecular Weight: 186.23
• Mol File: 1009-01-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methanesulfonic acid 2-methylphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonic acid 2-methylphenyl ester(1009-01-4)
• EPA Substance Registry System: Methanesulfonic acid 2-methylphenyl ester(1009-01-4)

Safety Data

• Hazardous Substances Data: 1009-01-4(Hazardous Substances Data)

Usage

General Description

Methanesulfonic acid 2-methylphenyl ester, also known as toluenesulfonic acid methyl ester, is a clear, colorless liquid with a sweet, pungent odor. It is commonly used as a strong acid catalyst in various chemical reactions, such as esterifications, polymerizations, and alkylation reactions. This chemical is also utilized as a solvent and as an intermediate in the production of pharmaceuticals, dyes, and fragrances. It is important to handle this chemical with caution, as it can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Additionally, it is highly flammable and should be stored and handled in a well-ventilated area away from heat and sources of ignition.

Upstream product

• 95-48-7 ortho-cresol 
• 7143-01-3 Methanesulfonic anhydride 
• 75-75-2 methanesulfonic acid 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 89929-89-5 2-(3-methylphenyl)furan 
• 38527-54-7 2-(2'-methylphenyl)furan 
• 85553-43-1 2-(3-methylphenyl)thiophene 
• 99846-56-7 2-(2-methylphenyl)thiophene 
• 33388-67-9 (2-methyl-phenyl)-(piperidin-1-yl)methanone 
• 643-58-3 2-methylbiphenyl 
• 32959-60-7 2-(2-methylphenyl)-1,3-benzoxazole 
• 354120-51-7 5-methyl-2-(2-methylphenyl)-1,3-benzoxazole 
• 1390631-73-8 C₁₅H₁₇NO 
• 138350-83-1 N-(tert-butoxycarbonyl)-2-methylbenzylamine 
• 91994-11-5 5,5-dimethyl-2-(o-tolyl)-1,3,2-dioxaborinane 
• 95-47-6 o-xylene 
• 529-19-1 2-Methylbenzonitrile 

Relevant articles and documents

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Palladium-catalyzed intra-and intermolecular C-H arylation using mesylates: Synthetic scope and mechanistic studies

This paper describes the development of Pd-catalyzed inter-and intramolecular direct arylation using mesylates. Furthermore, a sequential mesylation/arylation protocol using phenols as substrates is described. These transformations are general with respect to the electronics of the C-H substrates and allow for the synthesis of diverse heterocyclic motifs in good yields. Both arenes and heteroarenes efficiently participate in these reactions. Preliminary mechanistic studies are presented for both inter-and intramolecular arylations.

Neopentylglycolborylation of aryl mesylates and tosylates catalyzed by Ni-based mixed-ligand systems activated with Zn

(Chemical Presented) The mixed-ligand system NiCl2(dppp)/dppf is shown to be an effective catalyst for the neopentylglycolborylation of ortho-, meta-, and para-substituted electron-rich and electrondeficient aryl mesylates and tosylates. The ad