100929-06-4Relevant academic research and scientific papers
Synthetic and immunological studies on clustered modes of mucin-related Tn and TF O-linked antigens: The preparation of a glycopeptide-based vaccine for clinical trials against prostate cancer
Kuduk, Scott D.,Schwarz, Jacob B.,Chen, Xiao-Tao,Glunz, Peter W.,Sames, Dalibor,Ragupathi, Govindaswami,Livingston, Philip O.,Danishefsky, Samuel J.
, p. 12474 - 12485 (2007/10/03)
The syntheses of two tumor-associated carbohydrate antigens, Tn and TF, have been achieved using glycal assembly and cassette methodologies. These synthetic antigens were subsequently clustered (c) and immunoconjugated to a carrier protein (KLH or BSA) or
Synthesis of glycopeptides with the TN and T antigen structures, and their coupling to bovine serum albumin.
Kunz,Birnbach,Wernig
, p. 207 - 223 (2007/10/02)
Glycopeptides with TN and T antigen structures that represent the N-terminal tripeptide of asialoglycophorin with blood-group M specificity have been synthesized using fluorenylmethoxycarbonyl (Fmoc) and 2-pyridylethoxycarbonyl (Pyoc) groups for amino pro
