100938-80-5

Basic information

• Product Name: N-(3,3-diphenylpropyl)benzamide
• Synonyms: N-(3,3-diphenylpropyl)benzamide
• CAS NO: 100938-80-5
• Molecular Formula: C₂₂H₂₁NO
• Molecular Weight: 315.40824
• Mol File: 100938-80-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(3,3-diphenylpropyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,3-diphenylpropyl)benzamide(100938-80-5)
• EPA Substance Registry System: N-(3,3-diphenylpropyl)benzamide(100938-80-5)

Safety Data

• Hazardous Substances Data: 100938-80-5(Hazardous Substances Data)

Usage

General Description

N-(3,3-diphenylpropyl)benzamide is a chemical compound that belongs to the benzamide class of organic compounds. It is characterized by the presence of a benzene ring attached to an amide functional group. N-(3,3-diphenylpropyl)benzamide is also known by its chemical formula C22H21NO and is widely used in the pharmaceutical industry for its potential medicinal properties. It has been studied for its potential anti-inflammatory and analgesic effects, making it a promising candidate for the development of new drugs to treat pain and inflammation-related conditions. Additionally, it has also been investigated for its potential use in various chemical synthesis reactions due to its unique structural properties.

Upstream product

• 71-43-2 benzene 
• 5586-73-2 3-diphenylpropyl amine 
• 65-85-0 benzoic acid 
• 7646-66-4 N-benzoylaziridine 
• 101-81-5 Diphenylmethane 

Downstream Products

• 13042-18-7 Fendiline 
• 495-69-2 Hippuric Acid 
• 119-61-9 benzophenone 

Relevant articles and documents

Site-Specific Oxidation of (sp3)C-C(sp3)/H Bonds by NaNO2/HCl

A site-specific oxidation of (sp3)C-C(sp3) and (sp3)C-H bonds in aryl alkanes by the use of NaNO2/HCl was explored. The method is chemical-oxidant-free, transition-metal-free, uses water as the solvent, and proceeds under mild conditions, making it valuable and attractive to synthetic organic chemistry.

Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase

Inhibition of soluble epoxide hydrolase (sEH) is hypothesized to lead to an increase in circulating levels of epoxyeicosatrienoic acids, resulting in the potentiation of their in vivo pharmacological properties. As part of an effort to identify inhibitors

Reactions with Azirridines, 36 Arene Hydrides 2 SN2 and SET Reactions of N-Acylaziridines with Diphenylmethanide and "Naphthalene Hydride" (Anion of Dihydronaphthalene)

Diphenylmethane is incompletely deprotonated by sodium naphthalenide in THF so that some "naphthalene hydride" 4 (anion of 1,4-dihydronaphthalene) remains present in the deprotonation equilibrium.The generated diphenylmethanide anion 3a reacts with the N-acylaziridines 6a-c to form the expected amidoethyl derivatives 7a-c in yields of less than 50percent.The formation of by-products from 6b and 6c can be rationalized on the basis of classic ionic mechanisms.However, for 6a the by-product N-ethylbenzamide clearly points to a SET mechanism with "naphthalene hydride" 4 as the electron source and with the radical 8 as a hydrogen source.