1010438-27-3

Basic information

• Product Name: N-benzyl-N-(3,3-dimethylbutyl)-4-methoxybenzylamine
• CAS NO: 1010438-27-3
• Molecular Weight: 311.467
• Mol File: 1010438-27-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(3,3-dimethylbutyl)-4-methoxybenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(3,3-dimethylbutyl)-4-methoxybenzylamine(1010438-27-3)
• EPA Substance Registry System: N-benzyl-N-(3,3-dimethylbutyl)-4-methoxybenzylamine(1010438-27-3)

Safety Data

• Hazardous Substances Data: 1010438-27-3(Hazardous Substances Data)

Upstream product

• 624-95-3 3,3-dimethylbutanol 
• 14429-02-8 benzyl-(4-methoxybenzyl)amine 

Relevant articles and documents

Cp*Ir-catalyzed N-alkylation of amines with alcohols. A versatile and atom economical method for the synthesis of amines

A versatile and highly atom economical catalytic system consisting of [Cp*IrCl2]2/NaHCO3 (Cp*=pentamethylcyclopentadienyl) for the N-alkylation of amines with primary and secondary alcohols as alkylating reagents has been developed. For example, the reaction of equimolar amounts of aniline and benzyl alcohol in the presence of [Cp*IrCl2]2 (1.0 mol % Ir) and NaHCO3 (1.0 mol %) in toluene at 110 °C gives N-benzylaniline in 94% yield. The present catalytic system is applicable to the N-alkylation of both primary and secondary amines, and only harmless water is produced as co-product. A wide variety of secondary and tertiary amines can be synthesized with high atom economy under mild and less-toxic conditions. One-pot sequential N-alkylation leading to tertiary amines bearing three different substituents is also described.