101067-62-3

Basic information

• Product Name: 2-phenyl-N-benzylidenethanolamine
• CAS NO: 101067-62-3
• Molecular Weight: 225.29
• Mol File: 101067-62-3.mol

Chemical Properties

• CAS DataBase Reference: 2-phenyl-N-benzylidenethanolamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-N-benzylidenethanolamine(101067-62-3)
• EPA Substance Registry System: 2-phenyl-N-benzylidenethanolamine(101067-62-3)

Safety Data

• Hazardous Substances Data: 101067-62-3(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 7568-93-6 2-Amino-1-phenylethanol 

Downstream Products

• 101067-57-6 3-phenoxy-4-phenylazetidin-2-one 
• 101067-55-4 1-(2-Bromo-2-phenyl-ethyl)-3-phenoxy-4-phenyl-azetidin-2-one 
• 101067-56-5 3-Phenoxy-4-phenyl-1-((E)-styryl)-azetidin-2-one 
• 97934-56-0 cis-3-phenoxy-4-phenyl-1-(2'-phenyl-2'-hydroxyethyl)azetidin-2-one 
• 102488-27-7 cis-3-phenoxy-4-phenyl-1-(2'-phenyl-2'-oxoethyl)azetidin-2-one 
• 97934-58-2 3-phenoxyacetyl-2,5-diphenyloxazolidine 
• 97934-56-0 1-(2-Hydroxy-2-phenyl-ethyl)-3-phenoxy-4-phenyl-azetidin-2-one 
• 101067-64-5 [1-Phenyl-meth-(Z)-ylidene]-(2-phenyl-2-trimethylsilanyloxy-ethyl)-amine 

Relevant articles and documents

Synthesis of β-lactams from acetic acids and imines induced by phenyl dichlorophosphate reagent

The development of a practical method for the preparation of vinylamino-β-lactams from Dane salts and Schiff bases is described. Among the reagents known to produce β-lactams from imines and acetic acids, only phenyl dichlorophosphate and 1-methyl-2-chloropyridinium iodide are suitable for the synthesis of vinylamino-β-lactams. Reaction of acetic acids with ethanolimine derivatives promoted by phenyl dichlorophosphate affords oxazolidines instead of β-lactams. Protection of the hydroxyl group as the trimethylsilyl ether in the starting Schiff bases provides a convenient route to the corresponding β-lactams instead of oxazolidines. Some observations on the scope of the method are made.