101067-57-6Relevant articles and documents
A new entry to N-unsubstituted β-lactams through a solid-phase approach
Dasgupta, Swapan K.,Banik, Bimal K.
, p. 9445 - 9447 (2007/10/03)
A remarkable new entry to N-unsubstituted β-lactams using rink resin as the solid-support has been developed.
Synthesis of N1-unsubstituted β-lactams via a facile deprotection of N1-[(α-thiophenyl)benzyl] group
Karupaiyan,Srirajan,Deshmukh,Bhawal
, p. 4375 - 4386 (2007/10/03)
A diastereoselective synthesis of (±) c/s-β-1actams (5 and 6) via cycloaddition reactions of N1-(α-thiophenyl)benzyl imines (3) with acid chlorides (4) in the presence of triethylamine is described. The deprotection of N1-(α-thiophenyl)benzyl group has been achieved by oxidation using potassium persulfate to give N-unsubstituted β-lactams (7) in good yields.
Stereocontrolled Synthesis of N-Vinyl-, N-(1'-Propenyl)-, and N-Unsubstituted-β-lactams from 2-Aza-1,3-butadienes via the Staudinger Reaction
Georg, Gunda I.,He, Ping,Kant, Joydeep,Wu, Zhi-jun
, p. 5771 - 5778 (2007/10/02)
2-Aza-1,3-butadienes 2 and 5 were synthesized in good yields and on a large scale.Reaction of 2 and 5 with acid chlorides in the presence of triethylamine (Staudinger reaction) resulted in the high-yielding formation of N-vinyl- and N-(1'-propenyl)-β-lact