101111-22-2Relevant academic research and scientific papers
Squalene synthase inhibitors: Isosteric replacements of the farnesyl chain of benzyl farnesyl amine
Brinkman, John A.,Damon, Robert E.,Fell, Jay B.,Perez, Lawerence B.,Scallen, Terence J.,Vedananda
, p. 2491 - 2494 (1996)
Squalene synthase catalyzes the committed step of cholesterol biosynthesis. We report here the synthesis and in vivo activity of a series of squalene synthase inhibitors that contain isosteric replacements for the farnesyl chain of the known inhibitor ben
Synthesis and Physicochemical Characterization of Fluorescent (E)-2-Stilbenyloxyalkylthiouracils and Isomer Differentiation using EIMS
Wyrzykiewicz, Elzbieta,Wendzonka, Monika
, p. 177 - 186 (2007/10/03)
Twelve new fluorescent (E)-2-stilbenyloxyalkylthiouracils and 6-methyluracils 5a-5I were prepared. EI induced mass spectral fragmentation of these compounds was investigated. Fragmentation pathways are proposed on the basis of accurate mass and metastable
