1011257-45-6

Basic information

• Product Name: (3R,4R)-1,3-dihydroxy-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one
• CAS NO: 1011257-45-6
• Molecular Weight: 346.34
• Mol File: 1011257-45-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,4R)-1,3-dihydroxy-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-1,3-dihydroxy-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one(1011257-45-6)
• EPA Substance Registry System: (3R,4R)-1,3-dihydroxy-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one(1011257-45-6)

Safety Data

• Hazardous Substances Data: 1011257-45-6(Hazardous Substances Data)

Upstream product

• 5455-87-8 4-methoxy-N-(4-nitrobenzylidene)aniline 
• 96-26-4 dihydroxyacetone 
• 62147-49-3 1,3-dihydroxyacetone dimer 
• 555-16-8 4-nitrobenzaldehdye 
• 104-94-9 4-methoxy-aniline 

Relevant articles and documents

Direct catalytic asymmetric three-component Mannich reactions with dihydroxyacetone: enantioselective synthesis of amino sugar derivatives

Highly enantioselective, amino acid-catalyzed, one-pot three-component asymmetric Mannich reactions between dihydroxyacetone, p-anisidine, and aldehydes are presented. The reactions proceeded with high chemo- and stereoselectivity and furnished the corresponding α,α′-dihydroxy-β-aminoketones in high yields with 82-95% ee.