5455-87-8

Basic information

• Product Name: (4-methoxyphenyl)-(4-nitrobenzylidene)amine
• Synonyms: (4-methoxyphenyl)-(4-nitrobenzylidene)amine;N-(4-methoxyphenyl)-1-(4-nitrophenyl)methanimine;(E)-4-Methoxy-N-(4-nitrobenzylidene)aniline
• CAS NO: 5455-87-8
• Molecular Formula: C₁₄H₁₂N₂O₃
• Molecular Weight: 256.25668
• Mol File: 5455-87-8.mol
• Article Data: 62

Chemical Properties

• Boiling Point: 432.1°C at 760 mmHg
• Flash Point: 215.1°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 2.87E-07mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: (4-methoxyphenyl)-(4-nitrobenzylidene)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxyphenyl)-(4-nitrobenzylidene)amine(5455-87-8)
• EPA Substance Registry System: (4-methoxyphenyl)-(4-nitrobenzylidene)amine(5455-87-8)

Safety Data

• Hazardous Substances Data: 5455-87-8(Hazardous Substances Data)

Usage

General Description

(4-methoxyphenyl)-(4-nitrobenzylidene)amine is an organic compound with the chemical formula C14H13N3O3. It is a yellow powder that is used in organic synthesis and chemical research. (4-methoxyphenyl)-(4-nitrobenzylidene)amine has potential applications in the development of pharmaceuticals and other chemical products. It is classified as an amine, which is a type of organic compound that contains a basic nitrogen atom. The presence of both a methoxy group and a nitro group in its structure makes this compound particularly useful for its reactivity and potential to participate in various chemical reactions. Overall, (4-methoxyphenyl)-(4-nitrobenzylidene)amine is an important chemical that has a range of potential applications in the field of chemistry and materials science.

InChI:InChI=1/C14H12N2O3/c1-19-14-8-4-12(5-9-14)15-10-11-2-6-13(7-3-11)16(17)18/h2-10H,1H3/b15-10+

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 104-94-9 4-methoxy-aniline 
• 105-45-3 acetoacetic acid methyl ester 
• 25174-15-6 (Z)-3-((4-methoxyphenyl)amino)-1-phenylprop-2-en-1-one 
• 528-75-6 2,4-dinitrobenzaldehyde 
• 100-52-7 benzaldehyde 
• 62-53-3 aniline 
• 2735-04-8 2,4-Dimethoxyaniline 
• 619-73-8 4-nitrobenzyl chloride 
• 103-82-2 phenylacetic acid 
• 599-67-7 1,1-diphenylethanol 
• 60-12-8 2-phenylethanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 

Downstream Products

• 64388-22-3 6-methoxy-2-(4-nitrophenyl)quinoline 
• 1227858-68-5 C₂₃H₂₁N₃O₆ 
• 1227858-70-9 C₂₁H₁₆ClN₃O₄ 
• 1227858-69-6 C₂₂H₁₉N₃O₅ 
• 16035-87-3 N-(p-nitrobenzyl)-p-anisidine 
• 38940-28-2 1-(4-methoxyphenylamino)-1-(4-nitrophenyl)pentan-3-one 
• 1207463-75-9 1-(4-methoxyphenylamino)-1-(4-nitrophenyl)hexan-3-one 
• 1110644-52-4 (3R,4R)-1,3-bis(benzyloxy)-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one 
• 1011257-45-6 (3R,4R)-1,3-dihydroxy-4-(p-methoxyphenylamino)-4-(p-nitrophenyl)butan-2-one 

Relevant articles and documents

Stereoselective synthesis of a new enantiopure tricyclic β-lactam derivative via a tricarbonyl(η6-arene)chromium(0) complex

The tricyclic β-lactam 5 has been synthesized both in racemic and enantiopure form starting from the enantiomerically pure tricarbonylchromium(0) complex 1. The synthetic sequence involves the stereoselective [2+2] cycloaddition of 1 with acetoxyacetylket

Nanomagnetic catalysis (Fe3O4@S–TiO2): a novel magnetically nano catalyst for the synthesis of new highly substituted tetrahydropyridine derivatives under solvent-free conditions

A novel nanomagnetic catalyst (Fe3O4@S–TiO2) was prepared by the hydrothermal method. At the first, Fe3O4 nanoparticles were synthesized, then iron oxide nanoparticles (IONPs) were dispersed in ethano

New compounds for a good old class: Synthesis of two Β-lactam bearing cephalosporins and their evaluation with a multidisciplinary approach

Antimicrobial resistance is spreading massively in the world and is becoming one of the main health threats of the 21st century. One of the possible strategies to overcome this problem is to modify the known classes of antibiotics in a rational way, with the aim of tuning their efficacy. In this paper, we present the synthesis and the evaluation of the biological activity of a series of two β-lactam bearing cephalosporin derivatives, in which an additional isolated azetidinone ring, bearing different substituents, is joined to the classical cephalosporanic nucleus by a chain of variable length. A computational approach has been also applied in order to predict the molecular interactions between some representative derivatives and selected penicillin-binding proteins, the natural targets of β-lactam antibiotics. All these derivatives are active against Gram-positive bacteria, with MIC100 comparable or even better than that of the reference antibiotic ceftriaxone, and show no or very low cytotoxic activity on different cell lines. Overall, these molecules appear to be able to exert their activity in particular against microorganisms belonging to some of the species more involved in the development of multidrug resistance.