101219-72-1

Basic information

• Product Name: (S)-1-(4-ethylphenyl)ethanol
• Synonyms: (S)-1-(4-ethylphenyl)ethanol
• CAS NO: 101219-72-1
• Molecular Formula: C10H14O
• Molecular Weight: 150.221
• Mol File: 101219-72-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 117 - 118 °C (13 mmHg)
• CAS DataBase Reference: (S)-1-(4-ethylphenyl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(4-ethylphenyl)ethanol(101219-72-1)
• EPA Substance Registry System: (S)-1-(4-ethylphenyl)ethanol(101219-72-1)

Safety Data

• Hazardous Substances Data: 101219-72-1(Hazardous Substances Data)

Upstream product

• 103966-60-5 1-(α-acetoxyethyl)-4-ethylbenzene 
• 40307-11-7 1-ethyl-4-ethynylbenzene 
• 105-05-5 1,4-diethylbenzene 
• 33967-18-9 1-(4-ethylphenyl)ethanol 
• 937-30-4 4-ethylacetophenone 
• 17279-31-1 (-)-(S)-N,N-dimethyl-1-phenylethylamine 
• 108-24-7 acetic anhydride 

Downstream Products

• 143394-10-9 (S,S)-α,α'-dimethyl-1,4-benzenedimethanol 

Relevant articles and documents

Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones

Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps. By combining [Ir(COD)Cl]2, 39 ketones including aromatic, heteroaryl, and alkyl ketones have been hydrogenated, all affording valuable chiral alcohols with 96.0-99.9% ee. A plausible reaction mechanism was discussed by NMR, HRMS, and DFT, and an activating model involving trihydride was verified.

Activity and specificity studies of the new thermostable esterase EstDZ2

In this paper, we study the activity and specificity of EstDZ2, a new thermostable carboxyl esterase of unknown function, which was isolated from a metagenome library from a Russian hot spring. The biocatalytic reaction employing EstDZ2 proved to be an efficient method for the hydrolysis of aryl p-, o- or m-substituted esters of butyric acid and esters of secondary alcohols. Docking studies revealed structural features of the enzyme that led to activity differences among the different substrates.

Transformation of Alkynes into Chiral Alcohols via TfOH-Catalyzed Hydration and Ru-Catalyzed Tandem Asymmetric Hydrogenation

A novel full atom-economic process for the transformation of alkynes into chiral alcohols by TfOH-catalyzed hydration coupled with Ru-catalyzed tandem asymmetric hydrogenation in TFE under simple conditions has been developed. A range of chiral alcohols was obtained with broad functional group tolerance, good yields, and excellent stereoselectivities.