101283-96-9

Upstream product

• 64-17-5 ethanol 
• 75385-92-1 (N,N-diphenylcarbamoyl) formyl chloride 
• 4755-77-5 Ethyl oxalyl chloride 
• 122-39-4 diphenylamine 

Downstream Products

• 129049-31-6 Diphenylamino-[(Z)-toluene-4-sulfonylimino]-acetic acid ethyl ester 
• 40686-26-8 4-Methyl-N,N-diphenylbenzamide 
• 18538-27-7 2-(diphenylamino)-2-oxoacetic acid 
• 124129-71-1 1-phenyl-3,3-di-p-tolyl-indolin-2-one 

Relevant academic research and scientific papers

Synthesis of 2,3-allenylamides utilizing [1,2]-phospha-Brook rearrangement and their application to gold-catalyzed cycloisomerization providing 2-aminofuran derivatives

An efficient synthetic method for 2,3-allenylamides having an oxygen functionality at the 2-position, which are difficult to access by conventional methods, was newly developed by utilizing the [1,2]-phospha-Brook rearrangement under Br?nsted base catalysis. Further manipulation of the 2,3-allenylamides via gold-catalyzed cycloisomerization enables the formation of 2-aminofuran derivatives.

Room-Temperature Decarboxylative Couplings of α-Oxocarboxylates with Aryl Halides by Merging Photoredox with Palladium Catalysis

Enabled by merging iridium photoredox catalysis and palladium catalysis, α-oxocarboxylate salts can be decarboxylatively coupled with aryl halides to generate aromatic ketones and amides at room temperature. DFT calculations suggest that this reaction proceeds through a Pd0-PdII-PdIII pathway, in which the PdIII intermediate is responsible for reoxidizing IrII to complete the IrIII-IrIII-IrII photoredox cycle. Like a mergin': Enabled by merging iridium photoredox catalysis and palladium catalysis, palladium-catalyzed decarboxylative coupling of α-oxocarboxylates with aryl halides can proceed at room temperature. DFT calculations suggest that a Pd0-PdII-PdIII catalytic cycle is merged with an IrIII-IrIII-IrII photoredox cycle, in which PdIII is responsible for oxidizing IrII to complete the photoredox cycle.