75385-92-1Relevant academic research and scientific papers
One-pot method for preparing 9 - acridine formic acid
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Paragraph 0018-0051, (2021/11/10)
The invention discloses a one-pot method for preparing 9 - acridine formic acid. After completion of the reaction, the unreacted oxalyl chloride and the reaction solvent are then distilled 5 - 10 °C off under reduced pressure until the reaction is complet
Design and synthesis of novel diphenyl oxalamide and diphenyl acetamide derivatives as anticonvulsants
Nikalje, Anna Pratima G.,Ghodke, Mangesh,Girbane, Amol
experimental part, p. 57 - 64 (2012/03/26)
A series of novel N1-substituted-N2,N 2-diphenyl oxalamides 3a-l were synthesized in good yield by stirring diphenylcarbamoyl formyl chloride (2) and various substituted aliphatic, alicyclic, aromatic, heterocyclic amines
MALE CONTRACEPTIVE
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Page/Page column 16-17, (2008/12/07)
A compound having formula (I). R1, R2, R3 and R4 are independently H or lower alkyl. R5 is aryl, heteroaryl, cycloalkyl, heterocycloalkyl, aryloxy, heteroaryloxy, cycloalkyloxy, heterocycloalkyloxy, a
Design, synthesis and?in?vivo anticonvulsant screening in?mice of?Novel phenylacetamides
Shindikar,Khan,Viswanathan
, p. 786 - 792 (2007/10/03)
A set of seven novel N-substituted 2-anilinophenylacetamides were designed by pharmacophore generation and using flexible alignment module of MOE software. The novel molecules were synthesized and screened for anticonvulsant activity in Swiss albino mice by MES and ScPTZ induced seizure tests. Test compounds were found to be potent in MES test. Compounds 12 and 14 were found to be more potent with ED50 values 24.0 and 8.0?mg kg-1, respectively, and their activity was comparable to standard drugs (Phenytoin, Carbamazepine). Test compounds did not show significant activity in ScPTZ test. Compounds 12 and 14 also exhibited higher protective indices (20.3 and 87.5, respectively) when assessed for neurotoxicity by rotarod test as compared to the standards.
Processes and polymorphs of diaryl-indolone galr3 antagonists
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Page/Page column 9-10, (2008/06/13)
This invention relates to crystalline forms, as well as an amorphous form of Compound I [1-phenyl-3-[[3-(trifluoromethyl)phenyl]imino]-1H-indol-2-one], the processes for their preparation, compositions containing the same and the therapeutic use of such c
PROCESSES AND POLYMORPHS OF DIARYL-INDOLONE GALR3 ANTAGONISTS
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Page 35; 38-39, (2008/06/13)
This invention relates to crystalline forms, as well as an amorphous form of Compound I [1-phenyl-3-[[3--(trifluoromethyl)phenyl]imino]-1H-indol-2-one], the processes for their preparation, compositions containing the same and the therapeutic use of such
Structure and Colour of P,P'-Tetra-t-butyl- and P,P'-Tetraphenyl Oxalic Acid Diphosphide and Derivatives
Becher, Hermann-J.,Fenske, Dieter,Langer, Ernst,Prokscha, Heinz
, p. 749 - 760 (2007/10/02)
The unexpected violet colour of P,P'-Tetraphenyl-oxalic acid diphosphide (3) stimulated the synthesis of the following derivatives: P,P'-tetra-t-butyl-oxalic acid diphosphide (2).N,P-tetraphenyl-oxalic acid amide phosphide (4) and P,α-triphenyl-glyoxylic
