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10130-87-7 Usage


For synthesis and pharmacological evaluation of sulfonamide derivatives of thiazolidin-4-ones 5-Bromo-2-methoxybenzenesulfonyl chloride is used.

Check Digit Verification of cas no

The CAS Registry Mumber 10130-87-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,3 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10130-87:
47 % 10 = 7
So 10130-87-7 is a valid CAS Registry Number.

10130-87-7 Well-known Company Product Price

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  • Alfa Aesar

  • (H34455)  2-Methoxybenzenesulfonyl chloride, 97%   

  • 10130-87-7

  • 250mg

  • 738.0CNY

  • Detail
  • Alfa Aesar

  • (H34455)  2-Methoxybenzenesulfonyl chloride, 97%   

  • 10130-87-7

  • 1g

  • 2044.0CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017


1.1 GHS Product identifier

Product name 2-Methoxybenzenesulfonyl chloride

1.2 Other means of identification

Product number -
Other names Benzenesulfonyl chloride, 2-methoxy-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10130-87-7 SDS

10130-87-7Relevant articles and documents

Sulfonyl halide synthesis by thiol oxyhalogenation using NBS/NCS – iPrOH

Silva-Cuevas, Carolina,Perez-Arrieta, Carlos,Polindara-García, Luis A.,Lujan-Montelongo, J. Armando

, p. 2244 - 2247 (2017)

A rapid and facile method provides a general route to sulfonyl bromides/chlorides by the oxidation of thiols using NXS – ROH (X?=?Br,Cl, R?=?iPr) as an oxyhalogenation reagent. Control experiments suggest that the alcohol component is the source of oxygen. The proposed method enable the access to structurally diverse sulfonyl bromides and chlorides including challenging examples, inaccessible by other synthetic methods.

Conversion of thiols into sulfonyl halogenides under aerobic and metal-free conditions

Jereb, Marjan,Hribernik, Luka

supporting information, p. 2286 - 2295 (2017/07/24)

An environmentally benign, metal-free synthesis of sulfonyl chlorides and bromides from thiols in the presence of ammonium nitrate, an aqueous solution of HCl and HBr and oxygen as a terminal oxidant was developed. The reactivity of various substituted thiophenols, benzylic-, aliphatic- and heteroaromatic thiols was examined. Ammonium nitrate served as a source of nitrogen oxides (NO/NO2), which are the crucial players in a redox-catalytic cycle. Sulfonyl chlorides and bromides were isolated without extraction and "filtered" over a short pad of silica gel; the use of solvents was greatly reduced in comparison with traditional isolation and purification. A "one-pot" protocol for the conversion of thiol into sulfonamide is also demonstrated. Scale-up experiments on the preparation of sulfonyl chloride and bromide are shown. A possible reaction pathway is discussed.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists


, (2008/06/13)

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.

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