101315-77-9

Basic information

• Product Name: (2-hydroxy-2-phenylpropyl)diphenylphosphine oxide
• Synonyms: (2-hydroxy-2-phenylpropyl)diphenylphosphine oxide
• CAS NO: 101315-77-9
• Molecular Weight: 336.37
• Mol File: 101315-77-9.mol

Chemical Properties

• CAS DataBase Reference: (2-hydroxy-2-phenylpropyl)diphenylphosphine oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (2-hydroxy-2-phenylpropyl)diphenylphosphine oxide(101315-77-9)
• EPA Substance Registry System: (2-hydroxy-2-phenylpropyl)diphenylphosphine oxide(101315-77-9)

Safety Data

• Hazardous Substances Data: 101315-77-9(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 101315-74-6 C₂₂H₃₃O₄PTi 
• 101315-76-8 C₂₆H₂₄ClCrO₂P₂ 
• 101248-14-0 C₂₅H₄₀O₅PTi^(1-)*Li⁽¹⁺⁾ 
• 2129-89-7 diphenyl(methyl)phosphine oxide 
• 108-86-1 bromobenzene 
• 2564-83-2 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical 
• 4559-70-0 Diphenylphosphine oxide 
• 98-83-9 isopropenylbenzene 

Downstream Products

• 42104-30-3 3-diphenylphosphinoyl-2-phenylprop-1-ene 

Relevant articles and documents

Dioxygen-induced oxidative activation of a P-H bond: Radical oxyphosphorylation of alkenes and alkynes toward β-oxy phosphonates

The dioxygen-induced radical oxyphosphorylation of alkenes and alkynes is presented, wherein a P-H bond was activated by molecular oxygen. Various β-oxy phosphonates could be facilely synthesized without the assistance of any transition metals or extra or

Phosphinoyl radical-initiated vicinal hydroxy-phosphorylation of alkenes

A protocol of Mn(OAc)3–mediated α,β-hydroxy-phosphorylation of alkenes with phosphorus-centered radicals generated from diphenylphosphine oxide is described. A combination of steric and electronic factors played an important role in this reacti

Copper-catalyzed direct hydroxyphosphorylation of electron-deficient alkenes with H-phosphine oxides and dioxygen

A copper-catalyzed direct hydroxyphosphorylation of electron-deficient alkenes with H-phosphine oxides and dioxygen is reported. The present reaction, proceeds under mild reaction conditions with good functional group tolerance, affording the facile and efficient synthesis of various β-hydroxyphosphine oxides in a scaled-up manner with moderate to good yields.

Catalyst-free direct difunctionalization of alkenes with H-phosphine oxides and dioxygen: A facile and green approach to β-hydroxyphosphine oxides

A simple and catalyst-free method has been developed for the construction of β-hydroxyphosphine oxides through direct difunctionalization of alkenes with H-phosphine oxides and dioxygen under mild conditions. Preliminary mechanistic studies indicated that the hydroxyl oxygen atom of β-hydroxyphosphine oxide originated from the dioxygen and the present reaction might involve a radical process.

Solvent-controlled direct radical oxyphosphorylation of styrenes mediated by Manganese(III)

Direct radical oxyphosphorylation of styrenes with diarylphosphine oxides and dialkyl phosphites mediated by Mn(OAc)3 is described. The solvent played a key role in this selective difunctionalization reaction.

A Simple Preparation of Vinyl- or Allyldiphenylphosphine Oxides

A general route to 2- or 2,2-substituted vinyldiphenylphosphine oxides or allyldiphenylphosphine oxides from ketones (or benzaldehyde) and the anion of methyldiphenylphosphine oxide is reported.The intially formed 2-hydroxyalkyldiphenylphosphine oxide is

New Reagents, XXXIX - Optimization of the Diastereo- and Aldehyde Selectivity of Horner-Type Reagents by Modification of the Structure

Introduction of an ortho-substituent in the phenyl residues of (α-lithiobutyl)diphenylphosphane oxide (7) increases the diastereoselectivity in the reaction with benzaldehyde. (α-Lithiobutyl)bis(2-methoxyphenyl)phosphane oxide (9) gave the erythro-product