101330-61-4Relevant articles and documents
A SHORT AND EFFICIENT SYNTHESIS OF PHENOLCARBOXAMIDES
Husson, Aline,Besselievre, Richard,Husson, Henri-Philippe
, p. 1031 - 1034 (2007/10/02)
The selective acylation of primary amine functions of polyamines with acylating agents derived from unprotected mono or o-dihydroxy aromatic acids is described.The key step of the method is the transient protection of the phenol groups during the preparation of the hydroxy-1-piperidine active esters.This method is especially applicable to the preparation of the radiolabelled polyamine derivatives.